Serological study of type A Indian foot-and-mouth disease virus isolates.

The antigenic relationship of sixty type A foot-and-mouth disease (FMD) viruses isolated between 1968 and 1993 has been determined with reference to a post-vaccinal bovine serum produced against type A IND 17/82. A micro-neutralization test and ELISA were used to compare isolates. Analysis of the results indicated that there was a positive correlation between the data from the two methods. The study indicated that type A IND 17/82 had a broad immunogenic spectrum and could be considered as a candidate vaccine strain for incorporation in FMD vaccines in India.