Literature DB >> 8825183

Three-dimensional quantitative structure-activity relationship for inhibitors of cytochrome P4502C9.

J P Jones1, M He, W F Trager, A E Rettie.   

Abstract

Mesh：

Substances：

Year:  1996        PMID： 8825183

Source DB:  PubMed          Journal:  Drug Metab Dispos        ISSN： 0090-9556            Impact factor:   3.922


× No keyword cloud information.
  8 in total

1.  In vitro permeability of poorly aqueous soluble compounds using different solubilizers in the PAMPA assay with liquid chromatography/mass spectrometry detection.

Authors:  Hanlan Liu; Chantel Sabus; Guy T Carter; Chao Du; Alex Avdeef; Mark Tischler
Journal:  Pharm Res       Date:  2003-11       Impact factor: 4.200

2.  Discriminant and quantitative PLS analysis of competitive CYP2C9 inhibitors versus non-inhibitors using alignment independent GRIND descriptors.

Authors:  Lovisa Afzelius; Collen M Masimirembwa; Anders Karlén; Tommy B Andersson; Ismael Zamora
Journal:  J Comput Aided Mol Des       Date:  2002-07       Impact factor: 3.686

3.  Line-walking method for predicting the inhibition of P450 drug metabolism.

Authors:  Matthew G Hudelson; Jeffrey P Jones
Journal:  J Med Chem       Date:  2006-07-13       Impact factor: 7.446

4.  Generation of in-silico cytochrome P450 1A2, 2C9, 2C19, 2D6, and 3A4 inhibition QSAR models.

Authors:  M Paul Gleeson; Andrew M Davis; Kamaldeep K Chohan; Stuart W Paine; Scott Boyer; Claire L Gavaghan; Catrin Hasselgren Arnby; Cecilia Kankkonen; Nan Albertson
Journal:  J Comput Aided Mol Des       Date:  2007-11-22       Impact factor: 3.686

Review 5.  Warfarin: history, tautomerism and activity.

Authors:  William R Porter
Journal:  J Comput Aided Mol Des       Date:  2010-03-30       Impact factor: 3.686

Review 6.  Cytochrome P4502C9: an enzyme of major importance in human drug metabolism.

Authors:  J O Miners; D J Birkett
Journal:  Br J Clin Pharmacol       Date:  1998-06       Impact factor: 4.335

Review 7.  Insights on cytochrome p450 enzymes and inhibitors obtained through QSAR studies.

Authors:  Jayalakshmi Sridhar; Jiawang Liu; Maryam Foroozesh; Cheryl L Klein Stevens
Journal:  Molecules       Date:  2012-08-03       Impact factor: 4.411

8.  Large-scale evaluation of cytochrome P450 2C9 mediated drug interaction potential with machine learning-based consensus modeling.

Authors:  Anita Rácz; György M Keserű
Journal:  J Comput Aided Mol Des       Date:  2020-03-27       Impact factor: 3.686
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.