Literature DB >> 8824191

Visualization of gene expression in living adult Drosophila.

M Calleja1, E Moreno, S Pelaz, G Morata.   

Abstract

To identify genes involved in the patterning of adult structures, Gal4-UAS (upstream activating site) technology was used to visualize patterns of gene expression directly in living flies. A large number of Gal4 insertion lines were generated and their expression patterns were studied. In addition to identifying several characterized developmental genes, the approach revealed previously unsuspected genetic subdivisions of the thorax, which may control the disposition of pattern elements. The boundary between two of these domains coincides with localized expression of the signaling molecule wingless.

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Year:  1996        PMID： 8824191     DOI： 10.1126/science.274.5285.252

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  159 in total

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9.  Discontinuities in Rap1 activity determine epithelial cell morphology within the developing wing of Drosophila.

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10.  Differing Strategies Despite Shared Lineages of Motor Neurons and Glia to Achieve Robust Development of an Adult Neuropil in Drosophila.

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