| Literature DB >> 8816374 |
R A Seder1, B L Kelsall, D Jankovic.
Abstract
IL-12 has been shown to be important in the generation of a functional Th1 response in animal models of both infectious and autoimmune disease. Furthermore, the role of IL-12 in the maintenance of the immune responses in these diseases is now emerging. Herein, we discuss the idea that memory responses for certain infections may be IL-12 independent, whereas memory responses for specific autoimmune diseases still require IL-12 to maintain a pathogenic response.Entities:
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Year: 1996 PMID： 8816374
Source DB: PubMed Journal: J Immunol ISSN： 0022-1767 Impact factor: 5.422