Pathophysiologic sequelae of intracranial disease.

A variety of intracranial diseases affect dogs and cats. Clinical signs often result not only from mechanical destruction of normal brain but also from associated pathophysiologic alterations induced secondary to the primary disease process. Effective management of intracranial disease requires recognition and treatment of the primary as well as of many of these secondary pathophysiologic sequelae. This article discusses the evolution, ramifications, diagnosis, and treatment of these pathophysiologic sequelae.