Literature DB >> 8812712

The O-2 Generating NADPH Oxidase of Phagocytes: Structure and Methods of Detection

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Abstract

The NADPH oxidase of phagocytic cells of the immune system plays an important role in the destruction of certain types of microbial pathogens during infections. Its inappropriate activation to release reactive oxidants may also contribute to host tissue damage in inflammatory diseases. In this review, the structure of the NADPH oxidase is described and many of the commonly used methods to detect its activation during the respiratory burst are listed. The advantages and disadvantages of each of these methods are critically discussed.

Entities:  

Year:  1996        PMID： 8812712     DOI： 10.1006/meth.1996.0064

Source DB:  PubMed          Journal:  Methods        ISSN： 1046-2023            Impact factor:   3.608


  12 in total

1.  Effects of staphylococcal enterotoxins on human neutrophil functions and apoptosis.

Authors:  D A Moulding; C Walter; C A Hart; S W Edwards
Journal:  Infect Immun       Date:  1999-05       Impact factor: 3.441

2.  Diadenosine polyphosphates induce intracellular Ca2+ mobilization in human neutrophils via a pertussis toxin sensitive G-protein.

Authors:  L Gasmi; A G McLennan; S W Edwards
Journal:  Immunology       Date:  1997-01       Impact factor: 7.397

3.  Luminol-amplified chemiluminescence detects mainly superoxide anion produced by human neutrophils.

Authors:  Samia Bedouhène; Farida Moulti-Mati; Margarita Hurtado-Nedelec; Pham My-Chan Dang; Jamel El-Benna
Journal:  Am J Blood Res       Date:  2017-07-25

4.  Insoluble and soluble immune complexes activate neutrophils by distinct activation mechanisms: changes in functional responses induced by priming with cytokines.

Authors:  G Fossati; R C Bucknall; S W Edwards
Journal:  Ann Rheum Dis       Date:  2002-01       Impact factor: 19.103

5.  Serum IL8 and mRNA level of CD11b in circulating neutrophils are increased in clinically amyopathic dermatomyositis with active interstitial lung disease.

Authors:  Jing Zou; Jie Chen; Qingran Yan; Qiang Guo; Chunde Bao
Journal:  Clin Rheumatol       Date:  2015-10-12       Impact factor: 2.980

Review 6.  The Potential Protective Effects of Polyphenols in Asbestos-Mediated Inflammation and Carcinogenesis of Mesothelium.

Authors:  Monica Benvenuto; Rosanna Mattera; Gloria Taffera; Maria Gabriella Giganti; Paolo Lido; Laura Masuelli; Andrea Modesti; Roberto Bei
Journal:  Nutrients       Date:  2016-05-09       Impact factor: 5.717

7.  Replication of Colonic Crohn's Disease Mucosal Escherichia coli Isolates within Macrophages and Their Susceptibility to Antibiotics.

Authors:  Sreedhar Subramanian; Carol L Roberts; C Anthony Hart; Helen M Martin; Steve W Edwards; Jonathan M Rhodes; Barry J Campbell
Journal:  Antimicrob Agents Chemother       Date:  2007-12-10       Impact factor: 5.191

8.  Anaplasma phagocytophilum reduces neutrophil apoptosis in vivo.

Authors:  Helena Scaife; Zerai Woldehiwet; C Anthony Hart; Steven W Edwards
Journal:  Infect Immun       Date:  2003-04       Impact factor: 3.441

9.  RNA-seq reveals activation of both common and cytokine-specific pathways following neutrophil priming.

Authors:  Helen L Wright; Huw B Thomas; Robert J Moots; Steven W Edwards
Journal:  PLoS One       Date:  2013-03-06       Impact factor: 3.240

Review 10.  Regulation of superoxide production in neutrophils: role of calcium influx.

Authors:  Sabrina Bréchard; Eric J Tschirhart
Journal:  J Leukoc Biol       Date:  2008-06-10       Impact factor: 4.962
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