| Literature DB >> 8812320 |
R M Dores1, D A Rubin, T W Quinn.
Abstract
Because of the high degree of primary sequence conservation in neuropeptides and low molecular weight polypeptide hormones, these polypeptides are not useful for constructing phylogenetic trees based on maximum parsimony analysis. This review focuses on the organization of neuropeptide and polypeptide hormone precursors and discusses strategies for aligning polypeptide precursors for phylogenetic analysis. Examples are provided to support the hypothesis that some neuropeptide and polypeptide precursors and some high molecular weight polypeptide hormones can be used as data sets for resolving deep divergences among vertebrate taxa.Mesh:
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Year: 1996 PMID: 8812320 DOI: 10.1006/gcen.1996.0088
Source DB: PubMed Journal: Gen Comp Endocrinol ISSN: 0016-6480 Impact factor: 2.822