| Literature DB >> 881194 |
H G Morse, J R Humbert, J J Hutter, A Robinson.
Abstract
Cultures of bone-marrow cells incubated for 5 h at 4 degrees had cells in metaphase with elongated chromosomes which were easily Giemsa banded. Colcemid was not necessary for metaphase arrest at this temperature. This technique made possible routine karyotyping of patients with leukemia and other hematological diseases in which the detection of aberrations was otherwise difficult.Entities:
Mesh：
Year: 1977 PMID： 881194 DOI： 10.1007/bf00293769
Source DB: PubMed Journal: Hum Genet ISSN： 0340-6717 Impact factor: 4.132