Literature DB >> 8808993

How fast do we age? Exercise performance over time as a biomarker.

W M Bortz1, W M Bortz1.   

Abstract

BACKGROUND: The rate of true chronologic functional change in humans has been previously obscured by inadvertent inclusion of data derived from sick or ill-conditioned individuals. The Masters athlete fulfills the need for a study cohort.
METHODS: Performance data by age were collected from recognized certifying organizations for running, rowing, and swimming events and plotted as percent decline from age 35, and a rate of decline of performance by age was plotted.
RESULTS: Close coincidence of the decay slopes of the events surveyed was observed. This rate is 0.5% per year. We argue that inasmuch as these strenuous events are subtended by most of the major body systems and are thereby rate-limited by them all, that no supporting system can decline faster than this rate.
CONCLUSION: The virtual identity of the performance slopes of the different athletic events with one another and to that of other functions including that of a central physiologic measure, VO2 max, indicates that 0.5% per year may be a basic biomarker of the aging process.

Entities:  

Mesh:

Year:  1996        PMID: 8808993     DOI: 10.1093/gerona/51a.5.m223

Source DB:  PubMed          Journal:  J Gerontol A Biol Sci Med Sci        ISSN: 1079-5006            Impact factor:   6.053


  13 in total

Review 1.  Biological basis of determinants of health.

Authors:  Walter M Bortz
Journal:  Am J Public Health       Date:  2005-03       Impact factor: 9.308

Review 2.  Adaptations to aerobic and resistance exercise in the elderly.

Authors:  Charles P Lambert; William J Evans
Journal:  Rev Endocr Metab Disord       Date:  2005-05       Impact factor: 6.514

3.  Are musculoskeletal complaints, related work impairment and desirable adjustments in work age-specific?

Authors:  I Zoer; M H W Frings-Dresen; J K Sluiter
Journal:  Int Arch Occup Environ Health       Date:  2013-08-31       Impact factor: 3.015

4.  Geriatrics: the effect of time in medicine.

Authors:  W M Bortz
Journal:  West J Med       Date:  1997-05

Review 5.  Masters athletes: factors affecting performance.

Authors:  L G Maharam; P A Bauman; D Kalman; H Skolnik; S M Perle
Journal:  Sports Med       Date:  1999-10       Impact factor: 11.136

Review 6.  Rate and mechanism of maximal oxygen consumption decline with aging: implications for exercise training.

Authors:  Steven Hawkins; Robert Wiswell
Journal:  Sports Med       Date:  2003       Impact factor: 11.136

7.  Muscle-specific inositide phosphatase (MIP/MTMR14) is reduced with age and its loss accelerates skeletal muscle aging process by altering calcium homeostasis.

Authors:  Sandra Romero-Suarez; Jinhua Shen; Leticia Brotto; Todd Hall; Chenglin Mo; Héctor H Valdivia; Jon Andresen; Michael Wacker; Thomas M Nosek; Cheng-Kui Qu; Marco Brotto
Journal:  Aging (Albany NY)       Date:  2010-08       Impact factor: 5.682

8.  Effects of age and gender on physical performance.

Authors:  Vanina Bongard; Ann Y McDermott; Gerard E Dallal; Ernst J Schaefer
Journal:  Age (Dordr)       Date:  2007-06-23

Review 9.  Organ reserve, excess metabolic capacity, and aging.

Authors:  Hani Atamna; Alfred Tenore; Forshing Lui; Joseph M Dhahbi
Journal:  Biogerontology       Date:  2018-01-15       Impact factor: 4.277

10.  Store-operated Ca(2+) entry (SOCE) contributes to normal skeletal muscle contractility in young but not in aged skeletal muscle.

Authors:  Angela M Thornton; Xiaoli Zhao; Noah Weisleder; Leticia S Brotto; Sylvain Bougoin; Thomas M Nosek; Michael Reid; Brian Hardin; Zui Pan; Jianjie Ma; Jerome Parness; Marco Brotto
Journal:  Aging (Albany NY)       Date:  2011-06       Impact factor: 5.682

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