Literature DB >> 880755

Fractures in children treated with methotrexate for leukemia.

S Stanisavljevic, A L Babcock.   

Abstract

Multiple fractures occurred in 7 children treated with methotrexate for leukemia. Non-union or delayed union in spite of adequate immobilization also occurred in children on methotrexate. When the methotrexate was discontinued the fractures usually healed. Methotrexate appears to be a drug which inhibits osteogenesis, and may be promising in heterotopic ossification and related orthopedic conditions.

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Year:  1977        PMID: 880755

Source DB:  PubMed          Journal:  Clin Orthop Relat Res        ISSN: 0009-921X            Impact factor:   4.176


  13 in total

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Authors:  I Lopez; A L Buchman
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Review 2.  Topics in pediatric leukemia--acute lymphoblastic leukemia and late effects in long-term survivors.

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Journal:  MedGenMed       Date:  2005-03-07

Review 3.  [Immunosuppressive treatment and bone healing].

Authors:  Dagmar Horn; Christoph Klaas; Michael Raschke; Richard Stange
Journal:  Unfallchirurg       Date:  2019-07       Impact factor: 1.000

4.  Methotrexate osteopathy.

Authors:  A M Schwartz; J C Leonidas
Journal:  Skeletal Radiol       Date:  1984       Impact factor: 2.199

5.  A genetic factor associated with low final bone mineral density in children after a long-term glucocorticoids treatment.

Authors:  H-W Park; S Tse; W Yang; H W Kelly; S C Kaste; C-H Pui; M V Relling; K G Tantisira
Journal:  Pharmacogenomics J       Date:  2016-02-09       Impact factor: 3.550

6.  Reduced bone density at completion of chemotherapy for a malignancy.

Authors:  P Arikoski; J Komulainen; P Riikonen; J S Jurvelin; R Voutilainen; H Kröger
Journal:  Arch Dis Child       Date:  1999-02       Impact factor: 3.791

Review 7.  Osteoporosis in rheumatoid arthritis.

Authors:  Y Suzuki; Y Mizushima
Journal:  Osteoporos Int       Date:  1997       Impact factor: 4.507

8.  Methotrexate osteopathy in rheumatic disease.

Authors:  S J Preston; T Diamond; A Scott; M R Laurent
Journal:  Ann Rheum Dis       Date:  1993-08       Impact factor: 19.103

9.  Case report 669: Osteonecrosis of bone associated with intraarterial therapy using cisplatin.

Authors:  P Wuisman; R Erlemann; A Roessner; A Bosse; C Kusniez-Glaz
Journal:  Skeletal Radiol       Date:  1991       Impact factor: 2.199

Review 10.  Drug-induced disorders of bone metabolism. Incidence, management and avoidance.

Authors:  G Jones; P N Sambrook
Journal:  Drug Saf       Date:  1994-06       Impact factor: 5.606

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