Literature DB >> 8807072

Effects of roxithromycin and erythromycin on interleukin 8-induced neutrophil recruitment and goblet cell secretion in guinea pig tracheas.

J Tamaoki1, J Nakata, E Tagaya, K Konno.   

Abstract

Inhaled interleukin 8 caused an increase in goblet cell secretion in guinea pig tracheas, which was accompanied by mucosal infiltration of neutrophils. These responses were inhibited by pretreatment with roxithromycin or erythromycin in a dose-dependent fashion. Macrolides may thus be a value in protecting against neutrophil-associated airway hypersecretion.

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Year:  1996        PMID： 8807072      PMCID： PMC163405     

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  9 in total

1.  Goblet cells in the peripheral airways in chronic bronchitis.

Authors:  W M Thurlbeck; D Malaka; K Murphy
Journal:  Am Rev Respir Dis       Date:  1975-07

2.  Neutrophil elastase and cathepsin G stimulate secretion from cultured bovine airway gland serous cells.

Authors:  C P Sommerhoff; J A Nadel; C B Basbaum; G H Caughey
Journal:  J Clin Invest       Date:  1990-03       Impact factor: 14.808

3.  Erythromycin inhibits respiratory glycoconjugate secretion from human airways in vitro.

Authors:  S K Goswami; S Kivity; Z Marom
Journal:  Am Rev Respir Dis       Date:  1990-01

Review 4.  Neutrophil-activating peptide-1/interleukin 8, a novel cytokine that activates neutrophils.

Authors:  M Baggiolini; A Walz; S L Kunkel
Journal:  J Clin Invest       Date:  1989-10       Impact factor: 14.808

5.  Erythromycin-induced suppression of pulmonary antibacterial defenses. A potential mechanism of superinfection in the lung.

Authors:  S Nelson; W R Summer; P B Terry; G A Warr; G J Jakab
Journal:  Am Rev Respir Dis       Date:  1987-11

6.  Erythromycin inhibits Cl secretion across canine tracheal epithelial cells.

Authors:  J Tamaoki; K Isono; N Sakai; T Kanemura; K Konno
Journal:  Eur Respir J       Date:  1992-02       Impact factor: 16.671

7.  Macrolides and immunity: effects of erythromycin and spiramycin on human mononuclear cell proliferation.

Authors:  Y Roche; M A Gougerot-Pocidalo; M Fay; N Forest; J J Pocidalo
Journal:  J Antimicrob Chemother       Date:  1986-02       Impact factor: 5.790

8.  Neural control of goblet cell secretion in guinea pig airways.

Authors:  K Tokuyama; H P Kuo; J A Rohde; P J Barnes; D F Rogers
Journal:  Am J Physiol       Date:  1990-08

9.  Effect of clarithromycin on sputum production and its rheological properties in chronic respiratory tract infections.

Authors:  J Tamaoki; K Takeyama; E Tagaya; K Konno
Journal:  Antimicrob Agents Chemother       Date:  1995-08       Impact factor: 5.191
  9 in total
  5 in total

1.  Absolute bioavailability and intracellular pharmacokinetics of azithromycin in patients with cystic fibrosis.

Authors:  Paul Beringer; Kitty My Tu Huynh; Jane Kriengkauykiat; Luke Bi; Nils Hoem; Stan Louie; Emily Han; Thao Nguyen; Donald Hsu; Purush A Rao; Bertrand Shapiro; Mark Gill
Journal:  Antimicrob Agents Chemother       Date:  2005-12       Impact factor: 5.191

2.  [Clinical effect of azithromycin adjuvant therapy in children with bronchiolitis: a systematic review and Meta analysis].

Authors:  Si-Yi Che; Huan He; Yu Deng; En-Mei Liu
Journal:  Zhongguo Dang Dai Er Ke Za Zhi       Date:  2019-08

3.  Topical azithromycin and clarithromycin inhibit acute and chronic skin inflammation in sensitized mice, with apparent selectivity for Th2-mediated processes in delayed-type hypersensitivity.

Authors:  Vanesa Ivetić Tkalčević; Snježana Cužić; Miroslava Dominis Kramarić; Michael J Parnham; Vesna Eraković Haber
Journal:  Inflammation       Date:  2012-02       Impact factor: 4.092

Review 4.  Neutrophils and Asthma.

Authors:  Akira Yamasaki; Ryota Okazaki; Tomoya Harada
Journal:  Diagnostics (Basel)       Date:  2022-05-08

Review 5.  Using guinea pigs in studies relevant to asthma and COPD.

Authors:  Brendan J Canning; Yangling Chou
Journal:  Pulm Pharmacol Ther       Date:  2008-02-02       Impact factor: 3.410
  5 in total

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