Literature DB >> 8805617

A model for induction of T cell-independent humoral immunity in response to polysaccharide antigens.

C M Snapper1, J J Mond.   

Abstract

We provide a model for induction of T cell-independent, polysaccharide-specific Ig secretion in response to bacterial challenge. Two predominant pathways are defined that require the concerted action of multivalent membrane Ig cross-linking by the polysaccharide Ag with 1) various B cell-activating moieties contained within the bacterial pathogen and/or 2) cytokines, such as IFN-gamma and granulocyte-macrophage colony-stimulating factor produced by NK cells and macrophages, that become activated in a T cell-independent manner during bacterial infection.

Entities:  

Mesh：

Substances：

Year:  1996        PMID： 8805617

Source DB:  PubMed          Journal:  J Immunol        ISSN： 0022-1767            Impact factor:   5.422


  44 in total

1.  In vitro and in vivo neutralization of the relapsing fever agent Borrelia hermsii with serotype-specific immunoglobulin M antibodies.

Authors:  A G Barbour; V Bundoc
Journal:  Infect Immun       Date:  2001-02       Impact factor: 3.441

2.  Comparative analysis of antibody responses against HSP60, invariant surface glycoprotein 70, and variant surface glycoprotein reveals a complex antigen-specific pattern of immunoglobulin isotype switching during infection by Trypanosoma brucei.

Authors:  M Radwanska; S Magez; A Michel; B Stijlemans; M Geuskens; E Pays
Journal:  Infect Immun       Date:  2000-02       Impact factor: 3.441

3.  Trypanosomes expressing a mosaic variant surface glycoprotein coat escape early detection by the immune system.

Authors:  Melissa E Dubois; Karen P Demick; John M Mansfield
Journal:  Infect Immun       Date:  2005-05       Impact factor: 3.441

Review 4.  How Oxidized Low-Density Lipoprotein Activates Inflammatory Responses.

Authors:  Jillian P Rhoads; Amy S Major
Journal:  Crit Rev Immunol       Date:  2018       Impact factor: 2.214

5.  B-Cell deficiency predisposes mice to disseminating anaerobic infections: protection by passive antibody transfer.

Authors:  L Hou; H Sasakj; P Stashenko
Journal:  Infect Immun       Date:  2000-10       Impact factor: 3.441

Review 6.  Pharmacology of ribosomal immunotherapy.

Authors:  J Clot
Journal:  Drugs       Date:  1997       Impact factor: 9.546

Review 7.  Some thoughts on the response to antigens that are effector T-helper independent ('thymus independence')

Authors:  M Cohn
Journal:  Scand J Immunol       Date:  1997-12       Impact factor: 3.487

8.  CD40-CD40L independent Ig gene hypermutation suggests a second B cell diversification pathway in humans.

Authors:  S Weller; A Faili; C Garcia; M C Braun; F Le Deist F; G de Saint Basile G; O Hermine; A Fischer; C A Reynaud; J C Weill
Journal:  Proc Natl Acad Sci U S A       Date:  2001-01-30       Impact factor: 11.205

9.  Lysibodies are IgG Fc fusions with lysin binding domains targeting Staphylococcus aureus wall carbohydrates for effective phagocytosis.

Authors:  Assaf Raz; Anna Serrano; Christine Lawson; Maneesha Thaker; Tricia Alston; Stylianos Bournazos; Jeffrey V Ravetch; Vincent A Fischetti
Journal:  Proc Natl Acad Sci U S A       Date:  2017-04-20       Impact factor: 11.205

Review 10.  Clustered carbohydrates in synthetic vaccines.

Authors:  Francesco Peri
Journal:  Chem Soc Rev       Date:  2012-12-18       Impact factor: 54.564
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.