Literature DB >> 8804733

Identification of the GABAA receptor alpha-subunit mRNA in rat intestine.

D K Zeiter1, X Li, D L Broussard.   

Abstract

We investigated the expression of gamma-aminobutyric acid type A (GABAA) receptor alpha 1-, alpha 2- and alpha 3-subunit mRNAs in the rat intestine using reverse transcription and polymerase chain reaction. alpha 1- and alpha 3-, but not alpha 2-, subunit mRNAs were amplified from the proximal intestine, ileum, and colon. In-situ hybridization studies demonstrated the expression of alpha 1-subunit mRNA by myenteric neurons. GABA may be active via the GABAA receptor in the enteric nervous system.

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Year:  1996        PMID: 8804733     DOI: 10.1016/0169-328x(96)00077-0

Source DB:  PubMed          Journal:  Brain Res Mol Brain Res        ISSN: 0169-328X


  3 in total

1.  Age-related differences of γ-aminobutyric acid (GABA)ergic transmission in human colonic smooth muscle.

Authors:  Maria Grazia Zizzo; Adele Cicio; Stefania Raimondo; Riccardo Alessandro; Rosa Serio
Journal:  Neurogastroenterol Motil       Date:  2021-08-25       Impact factor: 3.960

2.  Molecular and functional diversity of GABA-A receptors in the enteric nervous system of the mouse colon.

Authors:  Mohsen Seifi; James F Brown; Jeremy Mills; Pradeep Bhandari; Delia Belelli; Jeremy J Lambert; Uwe Rudolph; Jerome D Swinny
Journal:  J Neurosci       Date:  2014-07-30       Impact factor: 6.167

3.  Changes in the mucosal barrier during acute and chronic Trichuris muris infection.

Authors:  S Z Hasnain; D J Thornton; R K Grencis
Journal:  Parasite Immunol       Date:  2011-01       Impact factor: 2.280

  3 in total

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