Literature DB >> 8804529

Solution-phase generation of tetraurea libraries.

G W Shipps1, U P Spitz, J Rebek.   

Abstract

Libraries of tetraureas tethered to a rigid core have been assembled. This simple, solution-phase methodology generates a defined, anticipated distribution of compounds. These conclusions are supported by synthesizing pure (homo) tetraurea xanthenes and by HPLC analysis of small 'microlibraries'.

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Year:  1996        PMID: 8804529     DOI: 10.1016/0968-0896(96)00059-4

Source DB:  PubMed          Journal:  Bioorg Med Chem        ISSN: 0968-0896            Impact factor:   3.641


  1 in total

1.  Synthesis and screening of small molecule libraries active in binding to DNA.

Authors:  G W Shipps; K E Pryor; J Xian; D A Skyler; E H Davidson; J Rebek
Journal:  Proc Natl Acad Sci U S A       Date:  1997-10-28       Impact factor: 11.205

  1 in total

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