Literature DB >> 8801638

Epidemiology of syphilis in the United States, 1941--1993.

A K Nakashima1, R T Rolfs, M L Flock, P Kilmarx, J R Greenspan.   

Abstract

BACKGROUND AND OBJECTIVES: The distribution and trends of syphilis are influenced by biologic factors, sexual behaviors, biomedical technology, availability of and access to health care, public health efforts, changes in population dynamics, and sociocultural factors. The objective of this article is to review the epidemiology of syphilis in the United States during the period 1941-1993 in the context of some of these factors. STUDY
DESIGN: Surveillance data on cases of syphilis and congenital syphilis reported by state and city health departments to the Centers for Disease Control and Prevention were analyzed to show distribution and trends by geographic location, racial and ethnic groups, gender, and age.
RESULTS: Historically, syphilis was distributed widely throughout the country and declined rapidly after the introduction of penicillin therapy and broad-based public health programs, attaining its lowest levels in the 1950s. However, in recent years, the disease has returned and become focused in the southern region and in urban areas outside that region. Rates of syphilis have remained highest in black Americans, and the most recent national epidemic of syphilis primarily involved them. Rates in white men were at intermediate levels during the early 1980s but have declined to low rates in the 1990s, possibly because of changes in behavior in response to the AIDS epidemic. Rates in white women and other racial and ethnic groups have remained low throughout the 1980s and 1990s.
CONCLUSIONS: Syphilis remains a significant problem in the United States, and its epidemiology is influenced by a complex combination of factors. To prevent and control syphilis effectively, public health practitioners must understand these factors and design programs and interventions that address the disease in the context of these factors.

Entities:  

Mesh:

Year:  1996        PMID: 8801638     DOI: 10.1097/00007435-199601000-00006

Source DB:  PubMed          Journal:  Sex Transm Dis        ISSN: 0148-5717            Impact factor:   2.830


  26 in total

1.  "Broken windows" and the risk of gonorrhea.

Authors:  D Cohen; S Spear; R Scribner; P Kissinger; K Mason; J Wildgen
Journal:  Am J Public Health       Date:  2000-02       Impact factor: 9.308

Review 2.  Syphilis: review with emphasis on clinical, epidemiologic, and some biologic features.

Authors:  A E Singh; B Romanowski
Journal:  Clin Microbiol Rev       Date:  1999-04       Impact factor: 26.132

3.  The control of syphilis, a contemporary problem: a historical perspective.

Authors:  T Green; M D Talbot; R S Morton
Journal:  Sex Transm Infect       Date:  2001-06       Impact factor: 3.519

4.  Membrane topology and cellular location of the Treponema pallidum glycerophosphodiester phosphodiesterase (GlpQ) ortholog.

Authors:  D V Shevchenko; T J Sellati; D L Cox; O V Shevchenko; E J Robinson; J D Radolf
Journal:  Infect Immun       Date:  1999-05       Impact factor: 3.441

5.  A community level syphilis prevention programme: outcome data from a controlled trial.

Authors:  M W Ross; N S Chatterjee; L Leonard
Journal:  Sex Transm Infect       Date:  2004-04       Impact factor: 3.519

Review 6.  Syphilis: the renaissance of an old disease with oral implications.

Authors:  Giuseppe Ficarra; Roman Carlos
Journal:  Head Neck Pathol       Date:  2009-07-22

7.  Identification of homologs for thioredoxin, peptidyl prolyl cis-trans isomerase, and glycerophosphodiester phosphodiesterase in outer membrane fractions from Treponema pallidum, the syphilis spirochete.

Authors:  D V Shevchenko; D R Akins; E J Robinson; M Li; O V Shevchenko; J D Radolf
Journal:  Infect Immun       Date:  1997-10       Impact factor: 3.441

8.  Using a Health in All Policies approach to address social determinants of sexually transmitted disease inequities in the context of community change and redevelopment.

Authors:  Holly Avey; Elizabeth Fuller; Jane Branscomb; Karen Cheung; Phillip Jackson Reed; Naima Wong; Michael Henderson; Samantha Williams
Journal:  Public Health Rep       Date:  2013-11       Impact factor: 2.792

Review 9.  Control of syphilis outbreaks in men who have sex with men: the role of screening in nonmedical settings.

Authors:  Carol Ciesielski; Richard H Kahn; Melanie Taylor; Kathleen Gallagher; Larry J Prescott; Susan Arrowsmith
Journal:  Sex Transm Dis       Date:  2005-10       Impact factor: 2.830

10.  Sociodemographic factors and the variation in syphilis rates among US counties, 1984 through 1993: an ecological analysis.

Authors:  P H Kilmarx; A A Zaidi; J C Thomas; A K Nakashima; M E St Louis; M L Flock; T A Peterman
Journal:  Am J Public Health       Date:  1997-12       Impact factor: 9.308

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