Literature DB >> 8801163

Retinoid differentiation therapy in promyelocytic leukemia.

C Chomienne1, P Fenaux, L Degos.   

Abstract

Acute promyelocytic leukemia (APL) is a specific type of acute myeloid leukemia characterized by the morphology of the blast cells, a specific t(15;17) translocation, and risks of definite coagulopathy. Recently this leukemia was further characterized by an exquisite sensitivity to all-trans retinoic acid's differentiation effect and the production of a fusion gene altering the gene of RARalpha and a novel gene PML. In vivo differentiation therapy with retinoids in APL patients follows strict guidelines related both to the APL cell and the biodisposal of all-trans retinoic acid.

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Year:  1996        PMID： 8801163     DOI： 10.1096/fasebj.10.9.8801163

Source DB:  PubMed          Journal:  FASEB J        ISSN： 0892-6638            Impact factor:   5.191


  17 in total

1.  The PML/RARalpha fusion protein inhibits tumor necrosis factor-alpha-induced apoptosis in U937 cells and acute promyelocytic leukemia blasts.

Authors:  U Testa; F Grignani; P Samoggia; C Zanetti; R Riccioni; F Lo Coco; D Diverio; N Felli; C G Passerini; M Grell; P G Pelicci; C Peschle
Journal:  J Clin Invest       Date:  1998-05-15       Impact factor: 14.808

2.  Physical and functional interactions between cellular retinoic acid binding protein II and the retinoic acid-dependent nuclear complex.

Authors:  L Delva; J N Bastie; C Rochette-Egly; R Kraïba; N Balitrand; G Despouy; P Chambon; C Chomienne
Journal:  Mol Cell Biol       Date:  1999-10       Impact factor: 4.272

3.  Knockdown of AKR1C3 exposes a potential epigenetic susceptibility in prostate cancer cells.

Authors:  Craig L Doig; Sebastiano Battaglia; Farhat L Khanim; Christopher M Bunce; Moray J Campbell
Journal:  J Steroid Biochem Mol Biol       Date:  2015-09-30       Impact factor: 4.292

4.  TGF-beta cooperates with TGF-alpha to induce the self-renewal of normal erythrocytic progenitors: evidence for an autocrine mechanism.

Authors:  O Gandrillon; U Schmidt; H Beug; J Samarut
Journal:  EMBO J       Date:  1999-05-17       Impact factor: 11.598

5.  The promyelocytic leukemia zinc finger protein affects myeloid cell growth, differentiation, and apoptosis.

Authors:  R Shaknovich; P L Yeyati; S Ivins; A Melnick; C Lempert; S Waxman; A Zelent; J D Licht
Journal:  Mol Cell Biol       Date:  1998-09       Impact factor: 4.272

6.  Epigenetic silencing of CRABP2 and MX1 in head and neck tumors.

Authors:  Marilia F Calmon; Rodrigo V Rodrigues; Carla M Kaneto; Ricardo P Moura; Sabrina D Silva; Louise Danielle C Mota; Daniel G Pinheiro; Cesar Torres; Alex F de Carvalho; Patrícia M Cury; Fabio D Nunes; Ines Nobuko Nishimoto; Fernando A Soares; Adriana M A da Silva; Luis P Kowalski; Helena Brentani; Cleslei F Zanelli; Wilson A Silva; Paula Rahal; Eloiza H Tajara; Dirce M Carraro; Anamaria A Camargo; Sandro R Valentini
Journal:  Neoplasia       Date:  2009-12       Impact factor: 5.715

7.  Transporter-to-trap conversion: a disulfide bond formation in cellular retinoic acid binding protein I mutant triggered by retinoic acid binding irreversibly locks the ligand inside the protein.

Authors:  Virginie Sjoelund; Igor A Kaltashov
Journal:  Biochemistry       Date:  2007-10-24       Impact factor: 3.162

8.  RARalpha-PLZF overcomes PLZF-mediated repression of CRABPI, contributing to retinoid resistance in t(11;17) acute promyelocytic leukemia.

Authors:  Fabien Guidez; Sarah Parks; Henna Wong; Jelena V Jovanovic; Ashley Mays; Amanda F Gilkes; Kenneth I Mills; Marie-Claude Guillemin; Robin M Hobbs; Pier Paolo Pandolfi; Hugues de Thé; Ellen Solomon; David Grimwade
Journal:  Proc Natl Acad Sci U S A       Date:  2007-11-13       Impact factor: 11.205

9.  Molecular cloning and characterization of an invertebrate cellular retinoic acid binding protein.

Authors:  S G Mansfield; S Cammer; S C Alexander; D P Muehleisen; R S Gray; A Tropsha; W E Bollenbacher
Journal:  Proc Natl Acad Sci U S A       Date:  1998-06-09       Impact factor: 11.205

10.  Dissection of the critical binding determinants of cellular retinoic acid binding protein II by mutagenesis and fluorescence binding assay.

Authors:  Chrysoula Vasileiou; Kin Sing Stephen Lee; Rachael M Crist; Soheila Vaezeslami; Sarah M Goins; James H Geiger; Babak Borhan
Journal:  Proteins       Date:  2009-08-01
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