Literature DB >> 8800190

It's happening again--another diethylene glycol mass poisoning.

P M Wax1.   

Abstract

What lessons have we learned? Certainly, the similarities among these DEG poisoning tragedies are striking. Their raison d'êrre, especially in the last few poisoning epidemics, appears to be financially driven. DEG, an inexpensive solvent, is more profitable to use than the more expensive propylene glycol or glycerin. Despite the world wide proliferation of chemicals, pharmaceutical regulation is carried out at a national level. Certainly this sort of poisoning is bound to occur again unless much stricter pharmaceutical manufacturing oversight is employed and enforced throughout the world. Developing countries with fewer resources to implement such quality control monitoring will continue to be at higher risk for such poisoning epidemics. For now, we need to remain vigilant or such history will continue to repeat itself.

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Year:  1996        PMID: 8800190     DOI: 10.3109/15563659609028010

Source DB:  PubMed          Journal:  J Toxicol Clin Toxicol        ISSN: 0731-3810


  2 in total

1.  Medical toxicology and public health--update on research and activities at the centers for disease control and prevention and the agency for toxic substances and disease registry.

Authors:  Joshua G Schier; Laura Conklin; Raquel Sabogal; Damon Dell'aglio; Carlos Sanchez; James Sejvar
Journal:  J Med Toxicol       Date:  2008-03

2.  Safety assessment of the pharmacological excipient, diethylene glycol monoethyl ether (DEGEE), using in vitro and in vivo systems.

Authors:  Sonal Srivastava; Sakshi Mishra; Jayant Dewangan; Aman Divakar; Nidhi Gupta; Navodayam Kalleti; Madhav Nilakanth Mugale; Sadan Kumar; Sharad Sharma; Srikanta Kumar Rath
Journal:  Daru       Date:  2019-04-18       Impact factor: 3.117

  2 in total

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