Literature DB >> 8798161

Measurement and calculation of heterogeneity correction factors for an Ir-192 high dose-rate brachytherapy source behind tungsten alloy and steel shields.

A S Kirov1, J F Williamson, A S Meigooni, Y Zhu.   

Abstract

Shields made of high atomic number material are commonly used in vaginal applicators with high dose-rate (HDR) 192Ir remotely afterloaded brachytherapy sources. However little data is available for the dose distribution around such shields. Heterogeneity correction factors (HCFs) are defined as the ratio of the dose to a point with the heterogeneity (shield) in place, divided by the dose to the same point with no heterogeneity. Using thermoluminescent dosimeters (TLDs) in solid water phantom we have measured the HCFs behind 6 and 20 mm diam tungsten alloy disks, 4 and 2 mm thick and a 4 mm thick steel disk, positioned 15 mm from the source. For each measurement point, the heterogeneity correction factors were also inferred from Monte Carlo simulations, which accurately modeled the experimental geometry. The agreement between measured and calculated HCFs on the average was within 6%. Tungsten alloy disks resulted in about two times greater dose reduction in water (HCF approximately 0.4, for 20 x 4 mm disk) than for a steel disk with the same dimensions (HCF approximately 0.85). Reducing the disk diameter to 6 mm increased the dose transmission up to about 25%. Increasing the source-to-detector distance from 4 to 7 cm caused a change in HCF from 2% to more than 20%, depending on disk material and diameter. The detector artifact effects arising from the finite size and different composition of the TLD chips were determined.

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Year:  1996        PMID: 8798161     DOI: 10.1118/1.597733

Source DB:  PubMed          Journal:  Med Phys        ISSN: 0094-2405            Impact factor:   4.071


  3 in total

1.  Estimating statistical uncertainty of Monte Carlo efficiency-gain in the context of a correlated sampling Monte Carlo code for brachytherapy treatment planning with non-normal dose distribution.

Authors:  Nitai D Mukhopadhyay; Andrew J Sampson; Daniel Deniz; Gudrun Alm Carlsson; Jeffrey Williamson; Alexandr Malusek
Journal:  Appl Radiat Isot       Date:  2011-09-29       Impact factor: 1.513

2.  An analytical model to determine interseed attenuation effect in low-dose-rate brachytherapy.

Authors:  Habib Safigholi; Dariush Sardari; Somaye Karimi Jashni; Seied Rabi Mahdavi; Ali S Meigooni
Journal:  J Appl Clin Med Phys       Date:  2013-05-06       Impact factor: 2.102

Review 3.  Review of clinical brachytherapy uncertainties: analysis guidelines of GEC-ESTRO and the AAPM.

Authors:  Christian Kirisits; Mark J Rivard; Dimos Baltas; Facundo Ballester; Marisol De Brabandere; Rob van der Laarse; Yury Niatsetski; Panagiotis Papagiannis; Taran Paulsen Hellebust; Jose Perez-Calatayud; Kari Tanderup; Jack L M Venselaar; Frank-André Siebert
Journal:  Radiother Oncol       Date:  2013-11-30       Impact factor: 6.280

  3 in total

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