Literature DB >> 8797556

Intraoperative ketorolac and posttonsillectomy bleeding.

J H Judkins1, T G Dray, R N Hubbell.   

Abstract

OBJECTIVE: To determine the occurrence of posttonsillectomy bleeding in patients who received intraoperative ketorolac tromethamine.
DESIGN: Retrospective analysis.
SETTING: Academic tertiary care center. PATIENTS: Three hundred eleven patients who underwent tonsillectomy in an 18-month period. MAIN OUTCOME MEASURE: Occurrence of bleeding complications in patients who received ketorolac during tonsillectomy.
RESULTS: Fifty-eight of 311 patients who underwent tonsillectomy received intraoperative ketorolac with an overall postoperative bleeding rate of 17%. This high rate of bleeding complications compares with 4.4% in the remaining 253 patients who received traditional opioid analgesics.
CONCLUSIONS: Until further controlled studies have been conducted, the use of ketorolac in patients undergoing tonsillectomy should be avoided because of the increased incidence of postoperative bleeding complications.

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Year:  1996        PMID: 8797556     DOI: 10.1001/archotol.1996.01890210017004

Source DB:  PubMed          Journal:  Arch Otolaryngol Head Neck Surg        ISSN: 0886-4470


  7 in total

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Authors:  C Litalien; E Jacqz-Aigrain
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Review 2.  Nonsteroidal anti-inflammatory drugs and perioperative bleeding in paediatric tonsillectomy.

Authors:  Sharon R Lewis; Amanda Nicholson; Mary E Cardwell; Gretchen Siviter; Andrew F Smith
Journal:  Cochrane Database Syst Rev       Date:  2013-07-18

Review 3.  Ketorolac. A reappraisal of its pharmacodynamic and pharmacokinetic properties and therapeutic use in pain management.

Authors:  J C Gillis; R N Brogden
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Review 4.  Ketorolac for postoperative pain management in children.

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Review 5.  Minimising the adverse effects of ketorolac.

Authors:  D I Reinhart
Journal:  Drug Saf       Date:  2000-06       Impact factor: 5.606

6.  Opioid-Sparing Anesthetic Technique for Pediatric Patients Undergoing Adenoidectomy: A Pilot Study.

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7.  The effectiveness of pregabalin for post-tonsillectomy pain control: a randomized controlled trial.

Authors:  Soo Seog Park; Dong-Hyun Kim; In-Chul Nam; Il-Hwan Lee; Jae-Woong Hwang
Journal:  PLoS One       Date:  2015-02-23       Impact factor: 3.240

  7 in total

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