| Literature DB >> 8795840 |
Abstract
Childhood narcolepsy is frequently under-diagnosed. Hypersomnolence may not always be accompanied by cataplexy, sleep paralysis, or hypnagogic hallucinations in the early stages. Pathophysiologic considerations revolve around an altered central nervous system catecholamine-acetylcholine balance. Both idiopathic and symptomatic forms have been described. Serial polysomnography and multiple sleep latency tests may be required to establish a definitive diagnosis. The long-term management requires the provision of both pharmacological and non-pharmacological forms of therapy.Entities:
Mesh:
Year: 1996 PMID: 8795840 DOI: 10.1016/s1071-9091(96)80027-1
Source DB: PubMed Journal: Semin Pediatr Neurol ISSN: 1071-9091 Impact factor: 1.636