Literature DB >> 8794009

Immunity to Lyme disease: protection, pathology and persistence.

K P Seiler1, J J Weis.   

Abstract

Persistence of the Lyme disease spirochete, Borrelia burgdorferi, in the presence of an active immune response has been well documented. Evidence from the past year indicates that modulation of surface antigens by the spirochete may be a major mechanism for evading the immune response.

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Year:  1996        PMID： 8794009     DOI： 10.1016/s0952-7915(96)80038-0

Source DB:  PubMed          Journal:  Curr Opin Immunol        ISSN： 0952-7915            Impact factor:   7.486


  24 in total

1.  PCR-Based quantification of Borrelia burgdorferi organisms in canine tissues over a 500-Day postinfection period.

Authors:  R K Straubinger
Journal:  J Clin Microbiol       Date:  2000-06       Impact factor: 5.948

2.  Ablation of interleukin-12 exacerbates Lyme arthritis in SCID mice.

Authors:  J Anguita; S Samanta; S W Barthold; E Fikrig
Journal:  Infect Immun       Date:  1997-10       Impact factor: 3.441

3.  Modulation of cytokine release in ex vivo-stimulated blood from borreliosis patients.

Authors:  I Diterich; L Härter; D Hassler; A Wendel; T Hartung
Journal:  Infect Immun       Date:  2001-02       Impact factor: 3.441

4.  Cryptic and exposed invariable regions of VlsE, the variable surface antigen of Borrelia burgdorferi sl.

Authors:  F T Liang; J M Nowling; M T Philipp
Journal:  J Bacteriol       Date:  2000-06       Impact factor: 3.490

5.  Lack of humoral immune protection against Treponema denticola virulence in a murine model.

Authors:  L Kesavalu; S C Holt; J L Ebersole
Journal:  Infect Immun       Date:  1999-11       Impact factor: 3.441

6.  Dual role of interleukin-10 in murine Lyme disease: regulation of arthritis severity and host defense.

Authors:  J P Brown; J F Zachary; C Teuscher; J J Weis; R M Wooten
Journal:  Infect Immun       Date:  1999-10       Impact factor: 3.441

7.  Protective niche for Borrelia burgdorferi to evade humoral immunity.

Authors:  Fang Ting Liang; Eric L Brown; Tian Wang; Renato V Iozzo; Erol Fikrig
Journal:  Am J Pathol       Date:  2004-09       Impact factor: 4.307

8.  Borrelia burgdorferi changes its surface antigenic expression in response to host immune responses.

Authors:  Fang Ting Liang; Jun Yan; M Lamine Mbow; Steven L Sviat; Robert D Gilmore; Mark Mamula; Erol Fikrig
Journal:  Infect Immun       Date:  2004-10       Impact factor: 3.441

Review 9.  Outer membrane proteins of pathogenic spirochetes.

Authors:  Paul A Cullen; David A Haake; Ben Adler
Journal:  FEMS Microbiol Rev       Date:  2004-06       Impact factor: 16.408

10.  The failure of immune response evasion by linear plasmid 28-1-deficient Borrelia burgdorferi is attributable to persistent expression of an outer surface protein.

Authors:  Monica E Embers; Xavier Alvarez; Tara Ooms; Mario T Philipp
Journal:  Infect Immun       Date:  2008-07-14       Impact factor: 3.441
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