Literature DB >> 8793528

Presentation of poisoned patients to accident and emergency departments in the north of England.

S H Thomas1, L Bevan, S Bhattacharyya, M G Bramble, K Chew, J Connolly, B Dorani, K H Han, J E Horner, A Rodgers, B Sen, B Tesfayohannes, H Wynne, D N Bateman.   

Abstract

1. A 12 week prospective survey of all patients of any age with confirmed or suspected poisoning presenting to six accident and emergency departments in the North East of England was performed to establish the local incidence and patterns of presentation of poisoning. 2. 945 episodes of poisoning involving 852 patients were recorded representing approximately 1.2% of all A&E presentations and suggesting an annual attendance rate of 2.7 per 1000 persons per year. 3. Attendance rates varied threefold between hospitals and were similar in males and females overall; between the ages of five and 14 attendances were more common in females (1.9 vs 0.6/10(3)/y) while between 0 and 4 y (3.1 vs 2.4) and 25 and 34 y (3.9 vs 2.9/10(3)/y) they were more common in males. 4. The median interval between poisoning and presentation was 2 h (mean 4.1 h) and only 19% of cases presented within 1 h. Presentation was most common between Friday evening and Tuesday morning and in the late afternoon and evening. 5. 6% of the patients presented more than once with poisoning during the study period and 37% had a past history of deliberate self-harm. The most common poisons involved were paracetamol (43%), opioids (15%) and benzodiazepines (15%). 6. The study illustrates the frequency of presentations of poisoning to A&E departments. The high rate of poisoning in young men and the increasing use of paracetamol are particular causes for concern.

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Year:  1996        PMID: 8793528     DOI: 10.1177/096032719601500602

Source DB:  PubMed          Journal:  Hum Exp Toxicol        ISSN: 0960-3271            Impact factor:   2.903


  16 in total

1.  "Late presenters" after paracetamol self poisoning.

Authors:  M P Bradley; J S Nguyen-Van-Tam; J C Pearson
Journal:  J Epidemiol Community Health       Date:  1998-11       Impact factor: 3.710

2.  TOXBASE: poisons information on the internet.

Authors:  D N Bateman; A M Good; W J Laing; C A Kelly
Journal:  Emerg Med J       Date:  2002-01       Impact factor: 2.740

3.  Paracetamol overdose: an evidence based flowchart to guide management.

Authors:  C I Wallace; P I Dargan; A L Jones
Journal:  Emerg Med J       Date:  2002-05       Impact factor: 2.740

4.  Measuring plasma paracetamol concentrations in all patients with drug overdose or altered consciousness: does it change outcome?

Authors:  P I Dargan; S Ladhani; A L Jones
Journal:  Emerg Med J       Date:  2001-05       Impact factor: 2.740

5.  Web based information on clinical toxicology for the United Kingdom: uptake and utilization of TOXBASE in 2000.

Authors:  D Nicholas Bateman; Alison M Good; Catherine A Kelly; William J Laing
Journal:  Br J Clin Pharmacol       Date:  2002-07       Impact factor: 4.335

6.  Deliberate self harm.

Authors:  A House; D Owens; L Patchett
Journal:  Qual Health Care       Date:  1999-06

7.  Effect of activated charcoal alone or given after gastric lavage in reducing the absorption of diazepam, ibuprofen and citalopram.

Authors:  O Lapatto-Reiniluoto; K T Kivistö; P J Neuvonen
Journal:  Br J Clin Pharmacol       Date:  1999-08       Impact factor: 4.335

8.  Acute intoxication cases admitted to the emergency department of a university hospital.

Authors:  Ertugrul Kaya; Aylin Yilmaz; Ayhan Saritas; Serdar Colakoglu; Davut Baltaci; Hayati Kandis; Ismail Hamdi Kara
Journal:  World J Emerg Med       Date:  2015

9.  Should a lower treatment line be used when treating paracetamol poisoning in patients with chronic alcoholism?: a case against.

Authors:  Paul I Dargan; Alison L Jones
Journal:  Drug Saf       Date:  2002       Impact factor: 5.606

10.  Demographics of toxic exposures presenting to three public hospital emergency departments in Singapore 2001-2003.

Authors:  R Ponampalam; Hock Heng Tan; Kee Chong Ng; Wee Yee Lee; Sau Chew Tan
Journal:  Int J Emerg Med       Date:  2009-02-04
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