Intersegmental phase lags in the lamprey spinal cord: experimental confirmation of the existence of a boundary region.

A critical feature of the motor pattern generated by the lamprey spinal cord is an intersegmental delay that is constant down the cord and scales with cycle duration. This has been modelled as the output of a chain of coupled oscillators, within a general mathematical framework developed by Kopell and Ermentrout (1986, 1988). The analysis predicts that for asymmetric coupling of equally-activated oscillators, the intersegmental phase lag will be uniform along the chain except in a boundary layer at one end. Here we provide experimental evidence that a boundary layer does occur at the rostral end of an isolated preparation of lamprey spinal cord. In the context of the mathematical analysis, this indicates that ascending coupling is dominant in the control of intersegmental phase lag in the lamprey.