Literature DB >> 8791809

Cultured rat hepatocytes.

E L LeCluyse1, P L Bullock, A Parkinson, J H Hochman.   

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Year:  1996        PMID： 8791809     DOI： 10.1007/978-1-4899-1863-5_9

Source DB:  PubMed          Journal:  Pharm Biotechnol        ISSN： 1078-0467


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  23 in total

1.  Integration of preclinical and clinical data with pharmacokinetic modeling and simulation to evaluate fexofenadine as a probe for hepatobiliary transport function.

Authors:  Brandon Swift; Xianbin Tian; Kim L R Brouwer
Journal:  Pharm Res       Date:  2009-06-04       Impact factor: 4.200

Review 2.  Sandwich-cultured hepatocytes: an in vitro model to evaluate hepatobiliary transporter-based drug interactions and hepatotoxicity.

Authors:  Brandon Swift; Nathan D Pfeifer; Kim L R Brouwer
Journal:  Drug Metab Rev       Date:  2010-08       Impact factor: 4.518

3.  Identification of hepatic phospholipidosis inducers in sandwich-cultured rat hepatocytes, a physiologically relevant model, reveals altered basolateral uptake and biliary excretion of anionic probe substrates.

Authors:  Brian C Ferslew; Kim L R Brouwer
Journal:  Toxicol Sci       Date:  2014-02-22       Impact factor: 4.849

4.  Towards personalized medicine with a three-dimensional micro-scale perfusion-based two-chamber tissue model system.

Authors:  Liang Ma; Jeremy Barker; Changchun Zhou; Wei Li; Jing Zhang; Biaoyang Lin; Gregory Foltz; Jenni Küblbeck; Paavo Honkakoski
Journal:  Biomaterials       Date:  2012-03-18       Impact factor: 12.479

5.  FGF15/FGFR4 integrates growth factor signaling with hepatic bile acid metabolism and insulin action.

Authors:  Dong-Ju Shin; Timothy F Osborne
Journal:  J Biol Chem       Date:  2009-02-23       Impact factor: 5.157

6.  Combination lopinavir and ritonavir alter exogenous and endogenous bile acid disposition in sandwich-cultured rat hepatocytes.

Authors:  LaToya M Griffin; Paul B Watkins; Cassandra H Perry; Robert L St Claire; Kim L R Brouwer
Journal:  Drug Metab Dispos       Date:  2012-10-22       Impact factor: 3.922

7.  Influence of seeding density and extracellular matrix on bile Acid transport and mrp4 expression in sandwich-cultured mouse hepatocytes.

Authors:  Brandon Swift; Kim L R Brouwer
Journal:  Mol Pharm       Date:  2010-04-05       Impact factor: 4.939

8.  P-glycoprotein expression, localization, and function in sandwich-cultured primary rat and human hepatocytes: relevance to the hepatobiliary disposition of a model opioid peptide.

Authors:  Keith A Hoffmaster; Ryan Z Turncliff; Edward L LeCluyse; Richard B Kim; Peter J Meier; Kim L R Brouwer
Journal:  Pharm Res       Date:  2004-07       Impact factor: 4.200

9.  Roles of mitophagy and the mitochondrial permeability transition in remodeling of cultured rat hepatocytes.

Authors:  Sara Rodriguez-Enriquez; Yoichiro Kai; Eduardo Maldonado; Robert T Currin; John J Lemasters
Journal:  Autophagy       Date:  2009-11-13       Impact factor: 16.016

10.  Sorafenib hepatobiliary disposition: mechanisms of hepatic uptake and disposition of generated metabolites.

Authors:  Brandon Swift; Noelia Nebot; Jin Kyung Lee; Tianxiang Han; William R Proctor; Dhiren R Thakker; Dieter Lang; Martin Radtke; Mark J Gnoth; Kim L R Brouwer
Journal:  Drug Metab Dispos       Date:  2013-03-12       Impact factor: 3.922
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