P J Wedlund1, G R Wilkinson. Show Affiliations » 1. College of Pharmacy, University of Kentucky 40536, USA.
Abstract
Entities: Gene
Mesh: See more » Aryl Hydrocarbon HydroxylasesCytochrome P-450 CYP2C19Cytochrome P-450 Enzyme System/analysisCytochrome P-450 Enzyme System/geneticsCytochrome P-450 Enzyme System/metabolismHumansIn Vitro TechniquesMephenytoin/analogs & derivativesMephenytoin/chemistryMephenytoin/metabolismMephenytoin/urineMixed Function Oxygenases/analysisMixed Function Oxygenases/geneticsMixed Function Oxygenases/metabolismOmeprazole/metabolismPhenotypePolymorphism, GeneticStereoisomerismSubstrate Specificity
Substances: See more » 4-hydroxymephenytoinCytochrome P-450 Enzyme SystemMixed Function OxygenasesAryl Hydrocarbon HydroxylasesCYP2C19 protein, humanCytochrome P-450 CYP2C19OmeprazoleMephenytoin
Year: 1996 PMID: 8791767 DOI: 10.1016/s0076-6879(96)72013-x
Source DB: PubMed Journal: Methods Enzymol ISSN: 0076-6879 Impact factor: 1.600