Literature DB >> 879129

Influence of carbon chain length of dietary fat on intestinal alkaline phosphatase in chylous ascites.

J R Malagelada, L L Stolbach, W G Linscheer.   

Abstract

The long-term effects of chain length of dietary fat on intestinal lymphatic transport of alkaline phosphatase were investigated in two patients with chylous ascites due to leakage of intestinal lymph into the peritoneal cavity. Substitution of a medium-chain triglyceride diet for long-chain triglyceride resulted in a parallel fall in triglyceride and the intestinal isoenzyme of alkaline phosphatase in chylous ascites. The concentrations of lymph triglyceride were linearly related to lymph intestinal alkaline phosphatase levels, suggesting a positive relation between absorption of long-chain triglycerides and transport of mucosal alkaline phosphatase into lymph.

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Year:  1977        PMID： 879129     DOI： 10.1007/bf01073082

Source DB:  PubMed          Journal:  Am J Dig Dis        ISSN： 0002-9211


  14 in total

1.  ALKALINE PHOSPHATASE ACTIVITY IN HUMAN THORACIC DUCT LYMPH.

Authors:  R BLOMSTRAND; B WERNER
Journal:  Acta Chir Scand       Date:  1965-02

2.  Origin of fat in chylous ascites of patients with liver cirrhosis.

Authors:  J R Malagelada; F L Iber; W G Linscheer
Journal:  Gastroenterology       Date:  1974-11       Impact factor: 22.682

3.  Chylous ascites. Management with medium-chain triglycerides and exacerbation by lymphangiography.

Authors:  L D Weinstein; G T Scanlon; T Hersh
Journal:  Am J Dig Dis       Date:  1969-07

4.  Studies of the immunologic defects associated with intestinal lymphangiectasia, with some observations on dietary control of chylous ascites.

Authors:  J E McGuigan; M L Purkerson; W L Trudeau; M L Peterson
Journal:  Ann Intern Med       Date:  1968-02       Impact factor: 25.391

5.  Metabolic variants of intestinal alkaline phosphatase in relation to fat absorption: in situ demonstration with the organ-specific inhibitors L-phenylalanine and L-homoarginine.

Authors:  M B Rufo; J R Malagelada; W G Linscheer; W H Fishman
Journal:  Histochemie       Date:  1973

6.  Role of intestinal alkaline phosphatase in fat transport.

Authors:  K C Lam; S P Mistilis
Journal:  Aust J Exp Biol Med Sci       Date:  1973-06

7.  Immunology and biochemistry of Regan isoenzyme of alkaline phosphatase in human cancer.

Authors:  W H Fishman; N R Inglis; S Green; C L Anstiss; N K Gosh; A E Reif; R Rustigian; M J Krant; L L Stolbach
Journal:  Nature       Date:  1968-08-17       Impact factor: 49.962

8.  Automated differential isoenzyme analysis. I. L-phenylalanine-sensitive isoenzymes of human serum alkaline phosphatase.

Authors:  W H Fishman; S Green
Journal:  Enzymologia       Date:  1967-08-31

9.  Increased lymph alkaline phosphatase after fat feeding: effects of medium chain triglycerides and inhibition of protein synthesis.

Authors:  R M Glickman; D H Alpers; G D Drummey; K J Isselbacher
Journal:  Biochim Biophys Acta       Date:  1970-02-24

10.  L-homoarginine; an inhibitor of serum "bone and liver" alkaline phosphatase.

Authors:  W Fishman; H G Sie
Journal:  Clin Chim Acta       Date:  1970-08       Impact factor: 3.786
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  1 in total

1.  Accelerated fat absorption in intestinal alkaline phosphatase knockout mice.

Authors:  Sonoko Narisawa; Lei Huang; Arata Iwasaki; Hideaki Hasegawa; David H Alpers; José Luis Millán
Journal:  Mol Cell Biol       Date:  2003-11       Impact factor: 4.272
  1 in total

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