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Literature DB >> 8788227

A review of dehydroepiandrosterone (DHEA).

Abstract

Dehydroepiandrosterone (DHEA) is quantitatively the most abundant hormone in humans and mammals, with a wide variety of physiological effects, including major regulatory effects upon the immune system. Two of the most striking aspects of DHEA are a steady decline in DHEA with age and a significant deficiency in DHEA in patients with several major diseases, including cancer, atherosclerosis, and Alzheimer's disease. The hormone is secreted in a non-sulfated (DHEA) and sulfated form (DHEA-S). The two are apparently interchangeable, and it appears likely that its physiological effects are achieved by derivative molecules that have yet to be identified.

Entities: Chemical Disease Species

Mesh：

Substances：
Dehydroepiandrosterone

Year: 1995 PMID： 8788227 DOI： 10.1007/bf02691603

Source DB: PubMed Journal: Integr Physiol Behav Sci ISSN： 1053-881X

31 in total

1. Reduction of atherosclerosis by administration of dehydroepiandrosterone. A study in the hypercholesterolemic New Zealand white rabbit with aortic intimal injury.

Authors: G B Gordon; D E Bush; H F Weisman
Journal: J Clin Invest Date: 1988-08 Impact factor: 14.808

2. Adaptation to chronic stress in military trainees. Adrenal androgens, testosterone, glucocorticoids, IGF-1, and immune function.

Authors: E Bernton; D Hoover; R Galloway; K Popp
Journal: Ann N Y Acad Sci Date: 1995-12-29 Impact factor: 5.691

3. Intracranial dehydroepiandrosterone blocks the activation of tryptophan hydroxylase in response to acute sound stress.

Authors: V B Singh; M Kalimi; T H Phan; M C Boadle-Biber
Journal: Mol Cell Neurosci Date: 1994-04 Impact factor: 4.314

4. Relationship of body fat percentage and fat distribution with dehydroepiandrosterone sulfate in premenopausal females.

Authors: D P Williams; T W Boyden; R W Pamenter; T G Lohman; S B Going
Journal: J Clin Endocrinol Metab Date: 1993-07 Impact factor: 5.958

6. Farmers' Cohort for Agricultural Work-Related Musculoskeletal Disorders (FARM) Study: Study Design, Methods, and Baseline Characteristics of Enrolled Subjects.

Authors: Hannae Jo; Sora Baek; Hee-Won Park; Sang-Ah Lee; Jiyoung Moon; Jae E Yang; Ki Sung Kim; Jee Yong Kim; Eun Kyoung Kang
Journal: J Epidemiol Date: 2015-08-01 Impact factor: 3.211

Review 7. Dehydroepiandrosterone and Erectile Function: A Review.

Authors: Ahmed I El-Sakka
Journal: World J Mens Health Date: 2018-05-11 Impact factor: 5.400

7 in total

A review of dehydroepiandrosterone (DHEA).

1. Reduction of atherosclerosis by administration of dehydroepiandrosterone. A study in the hypercholesterolemic New Zealand white rabbit with aortic intimal injury.

2. Adaptation to chronic stress in military trainees. Adrenal androgens, testosterone, glucocorticoids, IGF-1, and immune function.

3. Intracranial dehydroepiandrosterone blocks the activation of tryptophan hydroxylase in response to acute sound stress.

4. Relationship of body fat percentage and fat distribution with dehydroepiandrosterone sulfate in premenopausal females.

5. Endocrine status in stage II vs. advanced premenopausal and postmenopausal breast cancer patients.

Review 6. Dehydroepiandrosterone: the "missing link" between hyperinsulinemia and atherosclerosis?

7. Age-related alterations in pulsatile secretion of TSH: role of dopaminergic regulation.

8. The influence of age on endocrine responses to ultraendurance stress.

Review 9. Cancer chemoprevention with the adrenocortical steroid dehydroepiandrosterone and structural analogs.

10. A prospective study of dehydroepiandrosterone sulfate, mortality, and cardiovascular disease.

1. The impact of a new emotional self-management program on stress, emotions, heart rate variability, DHEA and cortisol.

Review 2. Through the Looking-Glass: Reevaluating DHEA Metabolism Through HSD3B1 Genetics.

3. Anterior pituitary, sex hormones, and keratoconus: Beyond traditional targets.

4. Digital Delivery of Meditative Movement Training Improved Health of Cigarette-Smoke-Exposed Subjects.

5. Dehydroepiandrosterone sulfate treatment of mice modulates infection with Schistosoma mansoni.

6. Farmers' Cohort for Agricultural Work-Related Musculoskeletal Disorders (FARM) Study: Study Design, Methods, and Baseline Characteristics of Enrolled Subjects.

Review 7. Dehydroepiandrosterone and Erectile Function: A Review.