Literature DB >> 8787854

Pharmacological blood-brain barrier modification for selective drug delivery.

T F Cloughesy1, K L Black.   

Abstract

Vasoactive agents have been identified through studies of peritumoral edema and effects on systemic capillaries. Abnormal blood-brain barrier or blood-tumor barrier can develop transient increases in permeability with the intraarterial delivery of vasoactive agents. Normal blood-brain barrier resists the effects of these compounds because of a biochemical barrier that may inactivate or become inert to vasoactive agents. Vasoactive compounds, including leukotrienes, bradykinin, and histamine appear to selectively increase permeability in abnormal brain capillaries. Intracarotid infusion of leukotrienes, bradykinin, and other vasoactive agents can increase drug delivery to diseased tissue.

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Year:  1995        PMID： 8787854     DOI： 10.1007/bf01060218

Source DB:  PubMed          Journal:  J Neurooncol        ISSN： 0167-594X            Impact factor:   4.130


  37 in total

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Authors:  P M Vanhoutte; W Auch-Schwelk; M L Biondi; R R Lorenz; V B Schini; M J Vidal
Journal:  Br J Clin Pharmacol       Date:  1989       Impact factor: 4.335

2.  Convection-enhanced delivery of macromolecules in the brain.

Authors:  R H Bobo; D W Laske; A Akbasak; P F Morrison; R L Dedrick; E H Oldfield
Journal:  Proc Natl Acad Sci U S A       Date:  1994-03-15       Impact factor: 11.205

3.  The role of arachidonic acid in vasogenic brain edema.

Authors:  P H Chan; R A Fishman
Journal:  Fed Proc       Date:  1984-02

4.  Synthesis of compounds with properties of leukotrienes C4 and D4 in gerbil brains after ischemia and reperfusion.

Authors:  M A Moskowitz; K J Kiwak; K Hekimian; L Levine
Journal:  Science       Date:  1984-05-25       Impact factor: 47.728

5.  Differential blood-brain barrier permeabilities to [14C]sucrose and [3H]inulin after osmotic opening in the rat.

Authors:  Y Z Ziylan; P J Robinson; S I Rapoport
Journal:  Exp Neurol       Date:  1983-03       Impact factor: 5.330

6.  Discriminative effect of gamma-glutamyl transpeptidase inhibitors on metabolism of leukotriene C4 in peritoneal cells.

Authors:  D Aharony; P Dobson
Journal:  Life Sci       Date:  1984-11-19       Impact factor: 5.037

7.  Effects of adrenal cortical steroids and osmotic blood-brain barrier opening on methotrexate delivery to gliomas in the rodent: the factor of the blood-brain barrier.

Authors:  E A Neuwelt; P A Barnett; D D Bigner; E P Frenkel
Journal:  Proc Natl Acad Sci U S A       Date:  1982-07       Impact factor: 11.205

8.  Intracarotid infusion of RMP-7, a bradykinin analog: a method for selective drug delivery to brain tumors.

Authors:  T Inamura; T Nomura; R T Bartus; K L Black
Journal:  J Neurosurg       Date:  1994-11       Impact factor: 5.115

9.  Central bradykininergic system in normotensive and hypertensive rats.

Authors:  A L Alvarez; A Delorenzi; D Santajuliana; S Finkielman; V E Nahmod; C J Pirola
Journal:  Clin Sci (Lond)       Date:  1992-05       Impact factor: 6.124

10.  Bradykinin selectively opens blood-tumor barrier in experimental brain tumors.

Authors:  T Inamura; K L Black
Journal:  J Cereb Blood Flow Metab       Date:  1994-09       Impact factor: 6.200
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7.  Selective targeting of brain tumors with gold nanoparticle-induced radiosensitization.

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Review 8.  Current approaches to enhance CNS delivery of drugs across the brain barriers.

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  8 in total

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