| Literature DB >> 8787816 |
J D Richmon1, K Fukuda, F R Sharp, L J Noble.
Abstract
The cellular response resulting from breakdown of the blood-brain barrier was evaluated 24 h after hyperosomotic infusion of mannitol into the internal carotid artery in the rat. Heat shock protein (HSP-70), a marker of cellular stress and/or injury, was induced in scattered patches of neurons and glia in regions of barrier breakdown. These findings suggest that osmotically induced breakdown of the blood-brain barrier may result in cell injury.Entities:
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Year: 1995 PMID： 8787816 DOI： 10.1016/0304-3940(95)12208-7
Source DB: PubMed Journal: Neurosci Lett ISSN： 0304-3940 Impact factor: 3.046