Literature DB >> 8786360

Toxigenic molds in water-damaged buildings: dechlorogriseofulvins from Memnoniella echinata.

B B Jarvis1, Y Zhou, J Jiang, S Wang, W G Sorenson, E L Hintikka, M Nikulin, P Parikka, R A Etzel, D G Dearborn.   

Abstract

An investigation of a cluster of cases of pulmonary hemosiderosis in infants in Cleveland, OH, led to the isolation of many isolates of Stachybotrys atra and two isolates of a related toxigenic fungus, Memnoniella echinata. M. echinata produces two cytotoxic trichothecene mycotoxins, trichodermol (1a) and trichodermin (1b), as well as several griseofulvins. Dechlorogriseofulvin (2a) and epidechlorogriseofulvin (2b) were the major compounds isolated. This is the first report of a fungus outside the Penicillium genus producing griseofulvins.

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Year:  1996        PMID: 8786360     DOI: 10.1021/np960395t

Source DB:  PubMed          Journal:  J Nat Prod        ISSN: 0163-3864            Impact factor:   4.050


  6 in total

1.  Identification of the viridicatumtoxin and griseofulvin gene clusters from Penicillium aethiopicum.

Authors:  Yit-Heng Chooi; Ralph Cacho; Yi Tang
Journal:  Chem Biol       Date:  2010-05-28

2.  Analysis of fungal flora in indoor dust by ribosomal DNA sequence analysis, quantitative PCR, and culture.

Authors:  M Pitkäranta; T Meklin; A Hyvärinen; L Paulin; P Auvinen; A Nevalainen; H Rintala
Journal:  Appl Environ Microbiol       Date:  2007-11-02       Impact factor: 4.792

3.  Study of toxin production by isolates of Stachybotrys chartarum and Memnoniella echinata isolated during a study of pulmonary hemosiderosis in infants.

Authors:  B B Jarvis; W G Sorenson; E L Hintikka; M Nikulin; Y Zhou; J Jiang; S Wang; S Hinkley; R A Etzel; D Dearborn
Journal:  Appl Environ Microbiol       Date:  1998-10       Impact factor: 4.792

Review 4.  Indoor mold, toxigenic fungi, and Stachybotrys chartarum: infectious disease perspective.

Authors:  D M Kuhn; M A Ghannoum
Journal:  Clin Microbiol Rev       Date:  2003-01       Impact factor: 26.132

5.  Volatile sesquiterpenes from Stachybotrys chartarum: Indicators for trichothecene producing mold species?

Authors:  K Wilkins
Journal:  Environ Sci Pollut Res Int       Date:  2000       Impact factor: 4.223

6.  Conservation of griseofulvin genes in the gsf gene cluster among fungal genomes.

Authors:  Parisa Aris; Lihong Yan; Yulong Wei; Ying Chang; Bihong Shi; Xuhua Xia
Journal:  G3 (Bethesda)       Date:  2022-02-04       Impact factor: 3.542

  6 in total

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