Literature DB >> 8786100

Molecular cloning and mapping of a human cDNA for cytosolic malate dehydrogenase (MDH1).

T Tanaka1, J Inazawa, Y Nakamura.   

Abstract

We have isolated a human cDNA encoding a protein of 334 amino acids that shows 96% identity in amino acid sequence to murine cytosolic malate dehydrogenase. Heart and skeletal muscle expressed this gene most highly among the adult human tissues examined by Northern blot analysis. By fluorescence in situ hybridization, we determined its chromosomal location to be 2p15.

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Year:  1996        PMID： 8786100     DOI： 10.1006/geno.1996.0087

Source DB:  PubMed          Journal:  Genomics        ISSN： 0888-7543            Impact factor:   5.736


  4 in total

1.  MDH1 deficiency is a metabolic disorder of the malate-aspartate shuttle associated with early onset severe encephalopathy.

Authors:  Melissa H Broeks; Hanan E Shamseldin; Amal Alhashem; Mais Hashem; Firdous Abdulwahab; Tarfa Alshedi; Iman Alobaid; Fried Zwartkruis; Denise Westland; Sabine Fuchs; Nanda M Verhoeven-Duif; Judith J M Jans; Fowzan S Alkuraya
Journal:  Hum Genet       Date:  2019-09-19       Impact factor: 4.132

2.  Gene expression profiling in human null cell pituitary adenoma tissue.

Authors:  Ji Hu; Huaidong Song; Xuanchun Wang; Ye Shen; Fengling Chen; Yu Liu; Shiqi Li; Yongfei Wang; Xuefei Shou; Yulin Zhang; Renming Hu
Journal:  Pituitary       Date:  2007       Impact factor: 4.107

3.  Acetylation of malate dehydrogenase 1 promotes adipogenic differentiation via activating its enzymatic activity.

Authors:  Eun Young Kim; Won Kon Kim; Hyo Jin Kang; Jeong-Hoon Kim; Sang J Chung; Yeon Soo Seo; Sung Goo Park; Sang Chul Lee; Kwang-Hee Bae
Journal:  J Lipid Res       Date:  2012-06-12       Impact factor: 5.922

4.  Upregulation of MDH1 acetylation by HDAC6 inhibition protects against oxidative stress-derived neuronal apoptosis following intracerebral hemorrhage.

Authors:  Miao Wang; Chao Zhou; Lu Yu; Delian Kong; Weijing Ma; Bingchen Lv; Yan Wang; Weifeng Wu; Mingyue Zhou; Guiyun Cui
Journal:  Cell Mol Life Sci       Date:  2022-06-09       Impact factor: 9.207
  4 in total

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