Literature DB >> 8784425

Pyralomicins, novel antibiotics from Microtetraspora spiralis. III. Biosynthesis of pyralomicin 1a.

N Kawamura1, R Sawa, Y Takahashi, T Sawa, H Naganawa, T Takeuchi.   

Abstract

The biosynthesis of pyralomicin 1a (1) was studied by feeding of 13C and 15N labeled compounds to the culture of Microtetraspora spiralis MI178-34F18. The result indicated that the benzopyranopyrrole unit of 1 was derived from two units of acetate, one unit of propionate and one unit of proline, and that the cyclitol unit of 1 was derived from glucose metabolites. And 4'-O-CH3 was derived from the S-CH3 group of methionine.

Entities:  

Mesh:

Substances:

Year:  1996        PMID: 8784425     DOI: 10.7164/antibiotics.49.657

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN: 0021-8820            Impact factor:   2.649


  2 in total

1.  Genetic insights into pyralomicin biosynthesis in Nonomuraea spiralis IMC A-0156.

Authors:  Patricia M Flatt; Xiumei Wu; Steven Perry; Taifo Mahmud
Journal:  J Nat Prod       Date:  2013-04-22       Impact factor: 4.050

Review 2.  Biosynthesis of unusual aminocyclitol-containing natural products.

Authors:  Taifo Mahmud; Patricia M Flatt; Xiumei Wu
Journal:  J Nat Prod       Date:  2007-07-28       Impact factor: 4.050

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.