Literature DB >> 8783196

Apoptosis--molecular mechanisms and biomedical implications.

D J McConkey1, B Zhivotovsky, S Orrenius.   

Abstract

Apoptosis is a distinct form of cell death of importance in tissue development and homeostasis and in several diseases. This review summarizes current knowledge about the regulation and molecular mechanisms of apoptosis and discusses the potential role of disregulated apoptosis in several major diseases. Finally, we speculate that modulation of apoptosis may be a target in future drug therapy.

Mesh：

Year:  1996        PMID： 8783196     DOI： 10.1016/0098-2997(95)00006-2

Source DB:  PubMed          Journal:  Mol Aspects Med        ISSN： 0098-2997


  12 in total

Review 1.  Therapeutic applications of bacterial pigments: a review of current status and future opportunities.

Authors:  Muhammad Numan; Samina Bashir; Roqayya Mumtaz; Sibgha Tayyab; Najeeb Ur Rehman; Abdul Latif Khan; Zabta Khan Shinwari; Ahmed Al-Harrasi
Journal:  3 Biotech       Date:  2018-04-04       Impact factor: 2.406

2.  Pulsatile shear stress leads to DNA fragmentation in human SH-SY5Y neuroblastoma cell line.

Authors:  D H Triyoso; T A Good
Journal:  J Physiol       Date:  1999-03-01       Impact factor: 5.182

Review 3.  Molecular pathogenesis of oral squamous carcinoma.

Authors:  H K Williams
Journal:  Mol Pathol       Date:  2000-08

4.  Enhanced anti-apoptosis and gut epithelium protection function of acidic fibroblast growth factor after cancelling of its mitogenic activity.

Authors:  Xiao-Bing Fu; Xiao-Kun Li; Tong Wang; Biao Cheng; Zhi-Yong Sheng
Journal:  World J Gastroenterol       Date:  2004-12-15       Impact factor: 5.742

Review 5.  Phytoconstituents as apoptosis inducing agents: strategy to combat cancer.

Authors:  Manish Kumar; Varinder Kaur; Subodh Kumar; Satwinderjeet Kaur
Journal:  Cytotechnology       Date:  2015-08-04       Impact factor: 2.058

6.  Lack of association between enhanced TRPM-2/clusterin expression and increased apoptotic activity in sex-hormone-induced prostatic dysplasia of the Noble rat.

Authors:  S M Ho; I Leav; S Ghatak; F Merk; V S Jagannathan; K Mallery
Journal:  Am J Pathol       Date:  1998-07       Impact factor: 4.307

7.  Co-Targeting Plk1 and DNMT3a in Advanced Prostate Cancer.

Authors:  Zhuangzhuang Zhang; Lijun Cheng; Qiongsi Zhang; Yifan Kong; Daheng He; Kunyu Li; Matthew Rea; Jianling Wang; Ruixin Wang; Jinghui Liu; Zhiguo Li; Chongli Yuan; Enze Liu; Yvonne N Fondufe-Mittendorf; Lang Li; Tao Han; Chi Wang; Xiaoqi Liu
Journal:  Adv Sci (Weinh)       Date:  2021-05-29       Impact factor: 17.521

8.  Miltefosine-induced apoptotic cell death on Leishmania major and L. tropica strains.

Authors:  Shahram Khademvatan; Mohammad Javad Gharavi; Fakher Rahim; Jasem Saki
Journal:  Korean J Parasitol       Date:  2011-03-18       Impact factor: 1.341

9.  Changes in endoplasmic reticulum luminal environment affect cell sensitivity to apoptosis.

Authors:  K Nakamura; E Bossy-Wetzel; K Burns; M P Fadel; M Lozyk; I S Goping; M Opas; R C Bleackley; D R Green; M Michalak
Journal:  J Cell Biol       Date:  2000-08-21       Impact factor: 10.539

10.  The HIV-1 vpr protein acts as a negative regulator of apoptosis in a human lymphoblastoid T cell line: possible implications for the pathogenesis of AIDS.

Authors:  L Conti; G Rainaldi; P Matarrese; B Varano; R Rivabene; S Columba; A Sato; F Belardelli; W Malorni; S Gessani
Journal:  J Exp Med       Date:  1998-02-02       Impact factor: 14.307
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