Literature DB >> 8782406

A new cytotoxic compound from a water extract of corn.

Y Hayashi1, N Ishihara, M Takahashi, E Fujii, K Uenakai, S Masada, I Ichimoto.   

Abstract

A new cytotoxic compound 2 was isolated from a water extract of corn germ. Structural elucidation by spectroscopic data and chemical evidence fully substantiated 2 to be 11 (E)-10-oxo-11-octadecen-13-olide. Compound 2 exhibited considerably strong cytotoxic activity against various cell lines with IC50 of 0.9-2.8 micrograms/ml.

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Year:  1996        PMID: 8782406     DOI: 10.1271/bbb.60.1115

Source DB:  PubMed          Journal:  Biosci Biotechnol Biochem        ISSN: 0916-8451            Impact factor:   2.043


  2 in total

1.  The lipoxygenase pathway in tulip (Tulipa gesneriana): detection of the ketol route.

Authors:  A N Grechkin; L S Mukhtarova; M Hamberg
Journal:  Biochem J       Date:  2000-12-01       Impact factor: 3.857

2.  Sacrolide A, a new antimicrobial and cytotoxic oxylipin macrolide from the edible cyanobacterium Aphanothece sacrum.

Authors:  Naoya Oku; Miyako Matsumoto; Kohsuke Yonejima; Keijiroh Tansei; Yasuhiro Igarashi
Journal:  Beilstein J Org Chem       Date:  2014-08-07       Impact factor: 2.883

  2 in total

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