| Literature DB >> 8782357 |
Abstract
This paper reviews various aspects of efficacy, and methods for assaying the potency of modified live viral vaccines. The pros and cons of parametric versus non-parametric methods for analysis of potency assays are discussed and critical levels of protection, as determined by the target(s) of vaccination, are exemplified. Recommendations are presented for designing potency assays on master virus seeds and vaccine batches.Mesh:
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Year: 1996 PMID: 8782357 DOI: 10.1016/0264-410x(96)83467-0
Source DB: PubMed Journal: Vaccine ISSN: 0264-410X Impact factor: 3.641