M P Askin1, B S Lewis. 1. Division of Gastroenterology, Mount Sinai Medical Center, New York, USA.
Abstract
BACKGROUND: This study assessed the long-term effectiveness of push enteroscopic cauterization of bleeding intestinal angiodysplasia. METHODS: We retrospectively reviewed the clinical course of patients who underwent push and sonde enteroscopy for obscure gastrointestinal bleeding and were diagnosed with intestinal angiodysplasias. RESULTS: One hundred twelve patients bleeding from small intestinal angiodysplasias were identified. After excluding those lost to follow-up (29), data were collected from 83 patients. Fifty-five patients (29 men; mean age, 73 years; mean units of packed red blood cells transfused, 21.4; average bleeding history, 22 months) were cauterized. Twenty-eight patients (12 men; mean age, 71; mean units of packed red blood cells transfused, 15.8; average bleeding history, 22 months) were not cauterized. The noncauterized group (follow-up, 26 +/- 14 months; mean +/- SD) continued to bleed, requiring 2.16 +/- 3.86 units of packed red blood cells transfused per month (units/month) before and 0.97 +/- 1.46 units/month after diagnosis (NS). The cauterized group (follow-up, 30 +/- 18 months) significantly improved, requiring 2.40 +/- 2.97 units/month before treatment and 0.32 +/- 0.91 units/month after cauterization (p < 0.0001, paired t test). CONCLUSION: Cauterization of endoscopically accessible small intestinal angiodysplasias may decrease rebleeding.
BACKGROUND: This study assessed the long-term effectiveness of push enteroscopic cauterization of bleeding intestinal angiodysplasia. METHODS: We retrospectively reviewed the clinical course of patients who underwent push and sonde enteroscopy for obscure gastrointestinal bleeding and were diagnosed with intestinal angiodysplasias. RESULTS: One hundred twelve patientsbleeding from small intestinal angiodysplasias were identified. After excluding those lost to follow-up (29), data were collected from 83 patients. Fifty-five patients (29 men; mean age, 73 years; mean units of packed red blood cells transfused, 21.4; average bleeding history, 22 months) were cauterized. Twenty-eight patients (12 men; mean age, 71; mean units of packed red blood cells transfused, 15.8; average bleeding history, 22 months) were not cauterized. The noncauterized group (follow-up, 26 +/- 14 months; mean +/- SD) continued to bleed, requiring 2.16 +/- 3.86 units of packed red blood cells transfused per month (units/month) before and 0.97 +/- 1.46 units/month after diagnosis (NS). The cauterized group (follow-up, 30 +/- 18 months) significantly improved, requiring 2.40 +/- 2.97 units/month before treatment and 0.32 +/- 0.91 units/month after cauterization (p < 0.0001, paired t test). CONCLUSION: Cauterization of endoscopically accessible small intestinal angiodysplasias may decrease rebleeding.
Authors: Teresa Pinto-Pais; Rolando Pinho; Adélia Rodrigues; Carlos Fernandes; Iolanda Ribeiro; José Fraga; João Carvalho Journal: United European Gastroenterol J Date: 2014-12 Impact factor: 4.623