| Literature DB >> 8778246 |
J A Hutter1, M Salman, W B Stavinoha, N Satsangi, R F Williams, R T Streeper, S T Weintraub.
Abstract
A new antiinflammatory agent identified as 8-[C-beta-D-[2-O-(E)-cinnamoyl]glucopyranosyl]-2- [(R)-2-hydroxypropyl]-7-methoxy-5-methylchromone (1) has been isolated from Aloe barbadensis Miller. At a dose of 200 microg/mouse ear, 1 exhibited topical antiinflammatory activity equivalent to 200 microg/ear of hydrocortisone. There was no reduction in thymus weight caused by treatment with 1 for any of the doses tested, while 200 microg/ear of hydrocortisone resulted in a 50% decrease in thymus weight.Entities:
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Year: 1996 PMID: 8778246 DOI: 10.1021/np9601519
Source DB: PubMed Journal: J Nat Prod ISSN: 0163-3864 Impact factor: 4.050