Literature DB >> 8778242

Three new cytotoxic sesterterpenes from the marine sponge Hyrtios cf. erectus.

G Ryu1, S Matsunaga, N Fusetani.   

Abstract

Three new cytotoxic sesterterpenes, 1-3, have been isolated from the marine sponge Hyrtios cf. erectus. Their structures have been determined by interpretation of NMR data. They exhibited cytotoxicity against P-388 murine leukemia cells with IC50 values of 0.4-2.1 micrograms/mL.

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Year:  1996        PMID： 8778242     DOI： 10.1021/np960130e

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  7 in total

Review 1.  Sesterterpenoids with Anticancer Activity.

Authors:  Antonio Evidente; Alexander Kornienko; Florence Lefranc; Alessio Cimmino; Ramesh Dasari; Marco Evidente; Véronique Mathieu; Robert Kiss
Journal:  Curr Med Chem       Date:  2015       Impact factor: 4.530

2.  Hainanerectamines A-C, alkaloids from the Hainan sponge Hyrtios erecta.

Authors:  Wen-Fei He; Duo-Qing Xue; Li-Gong Yao; Jing-Ya Li; Jia Li; Yue-Wei Guo
Journal:  Mar Drugs       Date:  2014-06-30       Impact factor: 5.118

3.  Cytotoxic sesterterpenoids isolated from the marine sponge Scalarispongia sp.

Authors:  Yeon-Ju Lee; Jeong-Woo Lee; Dong-Geun Lee; Hyi-Seung Lee; Jong Soon Kang; Jieun Yun
Journal:  Int J Mol Sci       Date:  2014-11-04       Impact factor: 5.923

4.  Antiproliferative Scalarane-Based Metabolites from the Red Sea Sponge Hyrtios erectus.

Authors:  Sameh S Elhady; Ahmed M Al-Abd; Ali M El-Halawany; Abdulrahman M Alahdal; Hashim A Hassanean; Safwat A Ahmed
Journal:  Mar Drugs       Date:  2016-07-08       Impact factor: 5.118

5.  Anti-Helicobacter, Antitubercular and Cytotoxic Activities of Scalaranes from the Red Sea Sponge Hyrtios erectus.

Authors:  Abdulrahman M Alahdal; Hani Z Asfour; Safwat A Ahmed; Ahmad O Noor; Ahmed M Al-Abd; Mahmoud A Elfaky; Sameh S Elhady
Journal:  Molecules       Date:  2018-04-23       Impact factor: 4.411

6.  Cytotoxic Scalarane Sesterterpenes from the Sponge Hyrtios erectus.

Authors:  Oh-Seok Kwon; Donghwa Kim; Chang-Kwon Kim; Jeongyoon Sun; Chung J Sim; Dong-Chan Oh; Sang Koo Lee; Ki-Bong Oh; Jongheon Shin
Journal:  Mar Drugs       Date:  2020-05-13       Impact factor: 5.118

7.  Molecular Docking and Dynamics Simulation Study of Hyrtios erectus Isolated Scalarane Sesterterpenes as Potential SARS-CoV-2 Dual Target Inhibitors.

Authors:  Sameh S Elhady; Reda F A Abdelhameed; Rania T Malatani; Abdulrahman M Alahdal; Hanin A Bogari; Ahmad J Almalki; Khadijah A Mohammad; Safwat A Ahmed; Amgad I M Khedr; Khaled M Darwish
Journal:  Biology (Basel)       Date:  2021-05-01
  7 in total

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