Literature DB >> 8777855

Relapsing Wegener's granulomatosis: successful treatment with cyclosporin-A.

C Georganas1, D Ioakimidis, C Iatrou, B Vidalaki, K Iliadou, P Athanassiou, T Kontomerkos.   

Abstract

We describe the case of a 32-year-old splenectomised man with severe Wegener's granulomatosis which was refractory to conventional treatment with oral cyclophosphamide and prednisolone. Remission was temporarily induced only with plasma exchange or i.v. immunoglobulin. Because of frequent relapses of the disease and cyclophosphamide side effects, he was started on treatment with cyclosporin-A and a long lasting remission was achieved.

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Year:  1996        PMID： 8777855     DOI： 10.1007/bf02230339

Source DB:  PubMed          Journal:  Clin Rheumatol        ISSN： 0770-3198            Impact factor:   2.980


  11 in total

Review 1.  Disease associations and pathogenic role of antineutrophil cytoplasmic autoantibodies in vasculitis.

Authors:  J C Jennette; R J Falk
Journal:  Curr Opin Rheumatol       Date:  1992-02       Impact factor: 5.006

2.  The American College of Rheumatology 1990 criteria for the classification of Wegener's granulomatosis.

Authors:  R Y Leavitt; A S Fauci; D A Bloch; B A Michel; G G Hunder; W P Arend; L H Calabrese; J F Fries; J T Lie; R W Lightfoot
Journal:  Arthritis Rheum       Date:  1990-08

3.  The treatment of Wegener's granulomatosis with trimethoprim/sulfamethoxazole: illusion or vision?

Authors:  R A DeRemee
Journal:  Arthritis Rheum       Date:  1988-08

4.  Cyclosporin in Wegener granulomatosis.

Authors:  F Gremmel; W Druml; P Schmidt; W Graninger
Journal:  Ann Intern Med       Date:  1988-03       Impact factor: 25.391

5.  Treatment of Wegener's granulomatosis with cyclosporin.

Authors:  J C Borleffs; R H Derksen; R J Hené
Journal:  Ann Rheum Dis       Date:  1987-02       Impact factor: 19.103

6.  Treatment of Wegener's granulomatosis with intermittent high-dose intravenous cyclophosphamide.

Authors:  G S Hoffman; R Y Leavitt; T A Fleisher; J R Minor; A S Fauci
Journal:  Am J Med       Date:  1990-10       Impact factor: 4.965

7.  Renal transplantation in Wegener's granulomatosis.

Authors:  W H Schmitt; M Haubitz; N Mistry; R Brunkhorst; B Erbslöh-Möller; W L Gross
Journal:  Lancet       Date:  1993-10-02       Impact factor: 79.321

Review 8.  New developments in the treatment of systemic vasculitis.

Authors:  W L Gross
Journal:  Curr Opin Rheumatol       Date:  1994-01       Impact factor: 5.006

Review 9.  Wegener's granulomatosis: prospective clinical and therapeutic experience with 85 patients for 21 years.

Authors:  A S Fauci; B F Haynes; P Katz; S M Wolff
Journal:  Ann Intern Med       Date:  1983-01       Impact factor: 25.391

10.  Influence of disease manifestation and antineutrophil cytoplasmic antibody titer on the response to pulse cyclophosphamide therapy in patients with Wegener's granulomatosis.

Authors:  E Reinhold-Keller; J Kekow; A Schnabel; W H Schmitt; M Heller; A Beigel; G Duncker; W L Gross
Journal:  Arthritis Rheum       Date:  1994-06
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  4 in total

1.  The efficacy of topical 0.05 % cyclosporine A in patients with dry eye disease associated with Sjögren's syndrome.

Authors:  Hülya Devecı; Senol Kobak
Journal:  Int Ophthalmol       Date:  2014-01-19       Impact factor: 2.031

2.  Primary Cutaneous Small Vessel Vasculitis.

Authors:  James P. Russell; Roger H. Weenig
Journal:  Curr Treat Options Cardiovasc Med       Date:  2004-04

3.  Microscopic polyangiitis necrotizing glomerulonephritis associated with pregnancy: case with a 20-year clinical course and review of the literature.

Authors:  Yoichi Oshima; Tatsuya Suwabe; Yuji Marui; Noriko Hayami; Eiko Hasegawa; Masayuki Yamanouchi; Rikako Hiramatsu; Keiichi Sumida; Masahiro Kawada; Akinari Sekine; Hiroki Mizuno; Masahiko Oguro; Junichi Hoshino; Naoki Sawa; Yasuo Ishii; Takeshi Fujii; Kenichi Ohashi; Kenmei Takaichi; Yoshifumi Ubara
Journal:  CEN Case Rep       Date:  2018-06-05

4.  Treatment of chronic dry eye: focus on cyclosporine.

Authors:  George D Kymionis; Dimitrios I Bouzoukis; Vassilios F Diakonis; Charalambos Siganos
Journal:  Clin Ophthalmol       Date:  2008-12
  4 in total

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