Literature DB >> 8777575

15-Hydroxyprostaglandin dehydrogenase.

C M Ensor1, H H Tai.   

Abstract

Relatively little is known about how 15-PGDH activity is regulated. Changes in 15-PGDH activity have been reported in response to physiological changes brought about by aging, pregnancy, hormonal changes, hypertension and smoking. In addition a large number of drugs have been shown to affect 15-PGDH activity both in vivo and in vitro. The availability of the 15-PGDH cDNA will be a valuable tool for studying how this enzyme is regulated. Isolation of the genomic DNA with its promoter regions has not yet been reported.

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Year:  1995        PMID： 8777575     DOI： 10.1016/0929-7855(95)00040-w

Source DB:  PubMed          Journal:  J Lipid Mediat Cell Signal        ISSN： 0929-7855


  25 in total

1.  UV radiation inhibits 15-hydroxyprostaglandin dehydrogenase levels in human skin: evidence of transcriptional suppression.

Authors:  Benjamin L Judson; Akira Miyaki; Vikram D Kekatpure; Baoheng Du; Patricia Gilleaudeau; Mary Sullivan-Whalen; Arash Mohebati; Sudhir Nair; Jay O Boyle; Richard D Granstein; Kotha Subbaramaiah; James G Krueger; Andrew J Dannenberg
Journal:  Cancer Prev Res (Phila)       Date:  2010-07-19

2.  Role of dihydroartemisinin in regulating prostaglandin E2 synthesis cascade and inflammation in endothelial cells.

Authors:  Jie Yin; Weiwei Xia; Yue Zhang; Guixia Ding; Lihong Chen; Guangrui Yang; Songming Huang; Zhanjun Jia; Aihua Zhang
Journal:  Heart Vessels       Date:  2018-05-23       Impact factor: 2.037

3.  Non-canonical WNT5A signaling up-regulates the expression of the tumor suppressor 15-PGDH and induces differentiation of colon cancer cells.

Authors:  Lubna M Mehdawi; Chandra Prakash Prasad; Roy Ehrnström; Tommy Andersson; Anita Sjölander
Journal:  Mol Oncol       Date:  2016-08-01       Impact factor: 6.603

4.  Genetic variation in prostaglandin E2 synthesis and signaling, prostaglandin dehydrogenase, and the risk of colorectal adenoma.

Authors:  Elizabeth M Poole; Li Hsu; Liren Xiao; Richard J Kulmacz; Christopher S Carlson; Peter S Rabinovitch; Karen W Makar; John D Potter; Cornelia M Ulrich
Journal:  Cancer Epidemiol Biomarkers Prev       Date:  2010-01-19       Impact factor: 4.254

5.  Hypoxia activates 15-PGDH and its metabolite 15-KETE to promote pulmonary artery endothelial cells proliferation via ERK1/2 signalling.

Authors:  Cui Ma; Yun Liu; Yanyan Wang; Chen Zhang; Hongmin Yao; Jun Ma; Lei Zhang; Dandan Zhang; Tingting Shen; Daling Zhu
Journal:  Br J Pharmacol       Date:  2014-07       Impact factor: 8.739

Review 6.  15-hydroxyprostaglandin dehydrogenase (15-PGDH) and lung cancer.

Authors:  Hsin-Hsiung Tai; Min Tong; Yunfei Ding
Journal:  Prostaglandins Other Lipid Mediat       Date:  2007-01-17       Impact factor: 3.072

7.  Involvement of PGE2 and PGDH but not COX-2 in thrombin-induced cortical neuron apoptosis.

Authors:  Lakshmi Thirumangalakudi; Haripriya Vittal Rao; Paula Grammas
Journal:  Neurosci Lett       Date:  2009-01-21       Impact factor: 3.046

8.  Analysis of genes isolated from plated hemocytes of the Pacific oyster, Crassostreas gigas.

Authors:  Steven Roberts; Giles Goetz; Samuel White; Frederick Goetz
Journal:  Mar Biotechnol (NY)       Date:  2008-07-12       Impact factor: 3.619

9.  NAD+-dependent 15-hydroxyprostaglandin dehydrogenase regulates levels of bioactive lipids in non-small cell lung cancer.

Authors:  Duncan Hughes; Taisuke Otani; Peiying Yang; Robert A Newman; Rhonda K Yantiss; Nasser K Altorki; Jeff L Port; Min Yan; Sanford D Markowitz; Madhu Mazumdar; Hsin-Hsiung Tai; Kotha Subbaramaiah; Andrew J Dannenberg
Journal:  Cancer Prev Res (Phila)       Date:  2008-09

10.  Cancer genomics identifies regulatory gene networks associated with the transition from dysplasia to advanced lung adenocarcinomas induced by c-Raf-1.

Authors:  Astrid Rohrbeck; Jürgen Borlak
Journal:  PLoS One       Date:  2009-10-08       Impact factor: 3.240
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