PURPOSE: The outcome of pregnancies resulting from assisted reproduction technology does not seem to differ from the outcome of those arising from spontaneous natural conception. METHODS: There is increased risk of chromosomal abnormality in spontaneous natural pregnancies resulting from consanguineous marriage, with consequent higher rates of miscarriage, stillbirth, and congenital abnormalities. RESULTS: This study has shown a trend of an increased miscarriage rate (but not statistically significant) in pregnancies achieved in infertile couples of consanguineous marriages by assisted reproductive technology. CONCLUSIONS: Selecting embryos for transfer on the basis of their morphology does not appear to reduce the risk of chromosomal abnormality in these couples.
PURPOSE: The outcome of pregnancies resulting from assisted reproduction technology does not seem to differ from the outcome of those arising from spontaneous natural conception. METHODS: There is increased risk of chromosomal abnormality in spontaneous natural pregnancies resulting from consanguineous marriage, with consequent higher rates of miscarriage, stillbirth, and congenital abnormalities. RESULTS: This study has shown a trend of an increased miscarriage rate (but not statistically significant) in pregnancies achieved in infertile couples of consanguineous marriages by assisted reproductive technology. CONCLUSIONS: Selecting embryos for transfer on the basis of their morphology does not appear to reduce the risk of chromosomal abnormality in these couples.
Authors: M Plachot; A Veiga; J Montagut; J de Grouchy; G Calderon; S Lepretre; A M Junca; J Santalo; E Carles; J Mandelbaum Journal: Hum Reprod Date: 1988-07 Impact factor: 6.918
Authors: H W Jones; A A Acosta; M C Andrews; J E Garcia; G S Jones; T Mantzavinos; J McDowell; B A Sandow; L Veeck; T W Whibley Journal: Fertil Steril Date: 1983-12 Impact factor: 7.329