Literature DB >> 8776946

Squalene synthase inhibitors: their potential as hypocholesterolaemic agents.

N S Watson1, P A Procopiou.   

Abstract

Entities:  

Mesh：

Substances：

Year:  1996        PMID： 8776946     DOI： 10.1016/s0079-6468(08)70308-4

Source DB:  PubMed          Journal:  Prog Med Chem        ISSN： 0079-6468


× No keyword cloud information.
  5 in total

1.  Natural Products and Their Mimics as Targets of Opportunity for Discovery.

Authors:  Stephen F Martin
Journal:  J Org Chem       Date:  2017-09-15       Impact factor: 4.354

2.  Binding modes of zaragozic acid A to human squalene synthase and staphylococcal dehydrosqualene synthase.

Authors:  Chia-I Liu; Wen-Yih Jeng; Wei-Jung Chang; Tzu-Ping Ko; Andrew H-J Wang
Journal:  J Biol Chem       Date:  2012-04-03       Impact factor: 5.157

3.  Enantioselective inhibition of squalene synthase by aziridine analogues of presqualene diphosphate.

Authors:  Ali Koohang; Jessica L Bailey; Robert M Coates; Hans K Erickson; David Owen; C Dale Poulter
Journal:  J Org Chem       Date:  2010-07-16       Impact factor: 4.354

4.  In vitro and in vivo activities of E5700 and ER-119884, two novel orally active squalene synthase inhibitors, against Trypanosoma cruzi.

Authors:  Julio A Urbina; Juan Luis Concepcion; Aura Caldera; Gilberto Payares; Cristina Sanoja; Takeshi Otomo; Hironobu Hiyoshi
Journal:  Antimicrob Agents Chemother       Date:  2004-07       Impact factor: 5.191

5.  Bis-cyclopropane analog of disorazole C1 is a microtubule-destabilizing agent active in ABCB1-overexpressing human colon cancer cells.

Authors:  Shaoyu Wu; Zhijian Guo; Chad D Hopkins; Ning Wei; Edward Chu; Peter Wipf; John C Schmitz
Journal:  Oncotarget       Date:  2015-12-01
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.