Literature DB >> 877548

Transport interaction of cystine and dibasic amino acids in renal brush border vesicles.

S Segal, P D McNamara, L M Pepe.   

Abstract

The uptake of cystine by vesicles prepared from rat kidney brush borders occurs by two distinct transport systems. The higher affinity system is inhibited by the dibasic amino acids lysine, arginine, and ornithine. The lower affinity system, unaffected by dibasic amino acids, appears to correspond to that observed by studying uptake of cystine by kidney slices.

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Year:  1977        PMID： 877548     DOI： 10.1126/science.877548

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  23 in total

1.  Cloning of a rat kidney cDNA that stimulates dibasic and neutral amino acid transport and has sequence similarity to glucosidases.

Authors:  R G Wells; M A Hediger
Journal:  Proc Natl Acad Sci U S A       Date:  1992-06-15       Impact factor: 11.205

2.  Comparative study of the uptake of L-cysteine and L-cystine in the renal proximal tubule.

Authors:  S Riahi-Esfahani; H Jessen; H Røigaard
Journal:  Amino Acids       Date:  1995-09       Impact factor: 3.520

3.  Molecular analysis of cystinuria in Libyan Jews: exclusion of the SLC3A1 gene and mapping of a new locus on 19q.

Authors:  R Wartenfeld; E Golomb; G Katz; S J Bale; B Goldman; M Pras; D L Kastner; E Pras
Journal:  Am J Hum Genet       Date:  1997-03       Impact factor: 11.025

4.  The molecular basis of cystinuria: the role of the rBAT gene.

Authors:  M Palacín; C Mora; J Chillarón; M J Calonge; R Estévez; D Torrents; X Testar; A Zorzano; V Nunes; J Purroy; X Estivill; P Gasparini; L Bisceglia; L Zelante
Journal:  Amino Acids       Date:  1996-06       Impact factor: 3.520

5.  Evidence suggesting that the minimal functional unit of a renal cystine transporter is a heterodimer and its implications in cystinuria.

Authors:  S S Tate
Journal:  Amino Acids       Date:  1996-06       Impact factor: 3.520

6.  Glutamine and glutamic acid uptake by rat renal brushborder membrane vesicles.

Authors:  S D Weiss; P D McNamara; L M Pepe; S Segal
Journal:  J Membr Biol       Date:  1978-09-29       Impact factor: 1.843

7.  Cloning and chromosomal localization of a human kidney cDNA involved in cystine, dibasic, and neutral amino acid transport.

Authors:  W S Lee; R G Wells; R V Sabbag; T K Mohandas; M A Hediger
Journal:  J Clin Invest       Date:  1993-05       Impact factor: 14.808

8.  Transport of L-cystine in isolated perfused proximal straight tubules.

Authors:  J A Schafer; M L Watkins
Journal:  Pflugers Arch       Date:  1984-06       Impact factor: 3.657

9.  Absence of a role of gamma-glutamyl transpeptidase in the transport of amino acids by rat renal brushborder membrane vesicles.

Authors:  B Y Hsu; J W Foreman; S M Corcoran; K Ginkinger; S Segal
Journal:  J Membr Biol       Date:  1984       Impact factor: 1.843

10.  Novel cystine transporter in renal proximal tubule identified as a missing partner of cystinuria-related plasma membrane protein rBAT/SLC3A1.

Authors:  Shushi Nagamori; Pattama Wiriyasermkul; Meritxell Espino Guarch; Hirohisa Okuyama; Saya Nakagomi; Kenjiro Tadagaki; Yumiko Nishinaka; Susanna Bodoy; Kazuaki Takafuji; Suguru Okuda; Junko Kurokawa; Ryuichi Ohgaki; Virginia Nunes; Manuel Palacín; Yoshikatsu Kanai
Journal:  Proc Natl Acad Sci U S A       Date:  2016-01-06       Impact factor: 11.205
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