OBJECTIVES: To evaluate the lipid parameters in normal Indian children. DESIGN: Cross-sectional. SETTING: Hospital based. METHODS: 410 children (siblings of hospitalized pediatric cases) between 3-12 years were evaluated for total plasma cholesterol (TC), triglycerides (TG) and high density lipoprotein cholesterol (HDL-C). The low density lipoprotein cholesterol (LDL-C) levels were derived from the above parameters using Fredrickson-Friedwald formula. RESULTS: No significant difference was found between the sexes in any of the lipid parameters studied. The mean values were: TC-134.5 mg/ dl, TG-91.1 mg/dl, HDL-C-34.15 mg/dl and LDL-C-80.1 mg/dl. The suggested cut off limits for these parameters were 190 mg/dl, 150 mg/dl, 20 mg/dl and 130 mg/d respectively. CONCLUSIONS: Lipid profile norms and cut off levels to define abnormalities for Indian children were recommended. The HDL-C levels were lower than western data.
OBJECTIVES: To evaluate the lipid parameters in normal Indian children. DESIGN: Cross-sectional. SETTING: Hospital based. METHODS: 410 children (siblings of hospitalized pediatric cases) between 3-12 years were evaluated for total plasma cholesterol (TC), triglycerides (TG) and high density lipoprotein cholesterol (HDL-C). The low density lipoprotein cholesterol (LDL-C) levels were derived from the above parameters using Fredrickson-Friedwald formula. RESULTS: No significant difference was found between the sexes in any of the lipid parameters studied. The mean values were: TC-134.5 mg/ dl, TG-91.1 mg/dl, HDL-C-34.15 mg/dl and LDL-C-80.1 mg/dl. The suggested cut off limits for these parameters were 190 mg/dl, 150 mg/dl, 20 mg/dl and 130 mg/d respectively. CONCLUSIONS:Lipid profile norms and cut off levels to define abnormalities for Indian children were recommended. The HDL-C levels were lower than western data.
Authors: Sun Eun Lee; Kerry Schulze; Christine P Stewart; Robert N Cole; Lee S-F Wu; Abdulkerim Eroglu; James D Yager; John Groopman; Parul Christian; Keith P West Journal: J Lipid Res Date: 2018-11-25 Impact factor: 5.922