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Literature DB >> 8768322

Cytotoxic azadirachtin-type limonoids from Melia azedarach.

K Takeya¹, Z S Qiao, C Hirobe, H Itokawa.

Abstract

Four new limonoids, 1-tigloyl-3,20-diacetyl-11-methoxymeliacarpinin, 3-tigloyl-1,20-diacetyl-11-methoxymeliacarpinin, 1-cinnamoyl-3-hydroxy-11-methoxymeliacarpinin, and 1-deoxy-3-methacrylyl-11-methoxymeliacarpinin, together with a known limonoid, 1-cinnamoyl-3-acetyl-11-methoxymeliacarpinin, were isolated from the extract of the root bark of Melia azedarach. The structures were elucidated by spectroscopy.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 1996 PMID： 8768322 DOI： 10.1016/0031-9422(96)00044-1

Source DB: PubMed Journal: Phytochemistry ISSN： 0031-9422 Impact factor: 4.072

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Cited

7 in total

Review 1. Insecticidal Triterpenes in Meliaceae: Plant Species, Molecules, and Activities: Part II (Cipadessa, Melia).

Authors: Meihong Lin; Xiaoyang Bi; Lijuan Zhou; Jiguang Huang
Journal: Int J Mol Sci Date: 2022-05-10 Impact factor: 6.208

2. Triterpenoids and Sterols from the Leaves and Twigs of Melia azedarach.

Authors: Wei-Ming Zhang; Jie-Qing Liu; Xing-Rong Peng; Luo-Sheng Wan; Zhi-Run Zhang; Zhong-Rong Li; Ming-Hua Qiu
Journal: Nat Prod Bioprospect Date: 2014-05-09

Review 3. Limonoids From the Genus Melia (Meliaceae): Phytochemistry, Synthesis, Bioactivities, Pharmacokinetics, and Toxicology.

Authors: Wenxiang Fan; Linhong Fan; Zhengtao Wang; Li Yang
Journal: Front Pharmacol Date: 2022-01-24 Impact factor: 5.810

4. Identification of the interacting proteins of Bambusa pervariabilis × Dendrocalamopsis grandis in response to the transcription factor ApCtf1β in Arthrinium phaeospermum.

Authors: Peng Yan; Jiawen Yu; Xinmei Fang; Shuying Li; Shan Han; Tiantian Lin; Yinggao Liu; Chunlin Yang; Fang He; Tianhui Zhu; Shujiang Li
Journal: Front Plant Sci Date: 2022-09-15 Impact factor: 6.627

Cytotoxic azadirachtin-type limonoids from Melia azedarach.

Review 1. Insecticidal Triterpenes in Meliaceae: Plant Species, Molecules, and Activities: Part II (Cipadessa, Melia).

2. Triterpenoids and Sterols from the Leaves and Twigs of Melia azedarach.

Review 3. Limonoids From the Genus Melia (Meliaceae): Phytochemistry, Synthesis, Bioactivities, Pharmacokinetics, and Toxicology.

4. Identification of the interacting proteins of Bambusa pervariabilis × Dendrocalamopsis grandis in response to the transcription factor ApCtf1β in Arthrinium phaeospermum.

5. The Toxicity and Anti-cancer Activity of the Hexane Layer of Melia azedarach L. var. japonica Makino's Bark Extract.

6. Meliacarpinin-Type Limonoids from the Bark of Melia toosendan.

7. Bio-selective hormonal breast cancer cytotoxic and antioxidant potencies of Melia azedarach L. wild type leaves.