Literature DB >> 8767886

[Comparison of the use of a vaccine and sequential antibiotic treatment in a herd infected with Mycoplasma hyopneumoniae].

A Le Grand1, M Kobisch.   

Abstract

The purpose of this study was to compare the efficacy of Mycoplasma hyopneumoniae vaccination with pulse medication in a pig herd chronically infected with Mycoplasma hyopneumoniae. Control groups of pigs were compared to vaccinated or treated groups. Medication and vaccination induced a significant reduction of pneumonia score (46.37% and 29.8% respectively, compared to 53.85% for control groups, p < 0.05). The treatment did not induce a significant reduction of the mean range of lung lesions (3.75) compared to the control groups (4.25). The mean range of lung lesions was significantly reduced by vaccine (3.06, p < 0.005) but not by treatment. Neither the medication nor the vaccination were able to clear M hyopneumoniae or Pasteurella multocida from lung tissue. In this herd, the vaccination had a beneficial effect on daily weight gain of pigs (695.9 g/day compared to 683.1 g/day for the control groups). The improvement of the age at slaughtering was 1.3 days for treated groups and 2.4 days for vaccinated groups compared to control groups. The vaccination induced a significant improvement in muscle rate (57.05%) compared to control groups (56.41%, p < 0.05) and to treated groups (56.21%, p < 0.001). In this herd infected with M hyopneumoniae, after allowing for treatment cost, manpower excepted, the increase in value was from -3 FF to -11 FF for the antibiotic treatment and +10.4 FF for the vaccination. From economical and medical points of view, the vaccination was preferable to the treatment under the conditions described in this study.

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Year:  1996        PMID: 8767886

Source DB:  PubMed          Journal:  Vet Res        ISSN: 0928-4249            Impact factor:   3.683


  3 in total

1.  Evolving importance of biologics and novel delivery systems in the face of microbial resistance.

Authors:  Terry L Bowersock
Journal:  AAPS PharmSci       Date:  2002

2.  Mycoplasma hyopneumoniae surface-associated proteases cleave bradykinin, substance P, neurokinin A and neuropeptide Y.

Authors:  Veronica Maria Jarocki; Benjamin Bernard Armando Raymond; Jessica Leigh Tacchi; Matthew Paul Padula; Steven Philip Djordjevic
Journal:  Sci Rep       Date:  2019-10-10       Impact factor: 4.379

Review 3.  Control of Mycoplasma hyopneumoniae infections in pigs.

Authors:  D Maes; J Segales; T Meyns; M Sibila; M Pieters; F Haesebrouck
Journal:  Vet Microbiol       Date:  2007-09-22       Impact factor: 3.293

  3 in total

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