Literature DB >> 87677

Genetic marker for insulin-dependent diabetes mellitus.

D Raum, C A Alper, R Stein, K H Gabbay.   

Abstract

A rare genetic type (Bf F1) of properdin factor B is found in 22.6% of patients with insulin-dependent diabetes mellitus but in only 1.9% of the general population, yielding a relative risk of 15.0. This indicates that a genetic locus for insulin-dependent diabetes mellitus is very close on chromosome 6 to Bf, and that Bf F1 is a marker for nearly 1 out of 4 insulin-dependent diabetic patients.

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Year:  1979        PMID: 87677     DOI: 10.1016/s0140-6736(79)91895-6

Source DB:  PubMed          Journal:  Lancet        ISSN: 0140-6736            Impact factor:   79.321


  28 in total

1.  Symposium on genetics.

Authors:  B J Culliton; W K Waterfall
Journal:  Br Med J       Date:  1979-10-27

2.  Polymorphism of MHC class III genes: definition of restriction fragment linkage groups and evidence for frequent deletions and duplications.

Authors:  N Ghanem; B Uring-Lambert; M Abbal; G Hauptmann; M P Lefranc; G Lefranc
Journal:  Hum Genet       Date:  1988-07       Impact factor: 4.132

3.  Molecular analysis distinguishes two HLA-DR3-bearing major histocompatibility complex extended haplotypes.

Authors:  M Z Wescott; Z L Awdeh; E J Yunis; C A Alper
Journal:  Immunogenetics       Date:  1987       Impact factor: 2.846

4.  HLA and complement allotypes in Type 1 (insulin-dependent) diabetes.

Authors:  J McCluskey; V J McCann; P H Kay; P J Zilko; F T Christiansen; G J O'Neill; R L Dawkins
Journal:  Diabetologia       Date:  1983-03       Impact factor: 10.122

5.  Extended major histocompatibility complex haplotypes in patients with gluten-sensitive enteropathy.

Authors:  C A Alper; E Fleischnick; Z Awdeh; A J Katz; E J Yunis
Journal:  J Clin Invest       Date:  1987-01       Impact factor: 14.808

6.  HLA genotype studies in juvenile insulin-dependent diabetes.

Authors:  I Deschamps; H Lestradet; C Bonaïti; M Schmid; M Busson; A Benajam; A Marcelli-Barge; J Hors
Journal:  Diabetologia       Date:  1980-09       Impact factor: 10.122

7.  The complement system in type 1 (insulin-dependent) diabetes.

Authors:  J A Charlesworth; V Timmermans; J Golding; L V Campbell; P W Peake; B A Pussell; D Wakefield; N Howard
Journal:  Diabetologia       Date:  1987-06       Impact factor: 10.122

8.  Association studies between Type 1 (insulin-dependent) diabetes and 27 genetic markers: lack of association between Type 1 diabetes and Kidd blood group.

Authors:  S E Hodge; C E Anderson; K Neiswanger; R Rubin; R S Sparkes; M C Sparkes; M Crist; M A Spence; P I Terasaki; D L Rimoin
Journal:  Diabetologia       Date:  1983-10       Impact factor: 10.122

9.  Susceptibility to IDDM is marked by MHC supratypes rather than individual alleles.

Authors:  H Kelly; V J McCann; P H Kay; R L Dawkins
Journal:  Immunogenetics       Date:  1985       Impact factor: 2.846

10.  The search for heterogeneity in insulin-dependent diabetes mellitus (IDDM): linkage studies, two-locus models, and genetic heterogeneity.

Authors:  S E Hodge; C E Anderson; K Neiswanger; R S Sparkes; D L Rimoin
Journal:  Am J Hum Genet       Date:  1983-11       Impact factor: 11.025

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