Literature DB >> 8767359

Anthelmintic activity of 6,7-diaryl-pteridines.

C Ochoa1, J Rodríguez, M L López García, A Ramón Martínez, M Mercedes Martínez.   

Abstract

In a search for new anthelmintic compounds, some 6,7-diaryl-pteridines were synthesized from the corresponding diaminopyrimidines and aromatic aldehydes. Their anthelmintic activity was tested in vitro against Caenorhabditis elegans and Heligmosomoides polygyrus and in vivo against Trichinella spiralis. Structure-activity relationships are discussed.

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Year:  1996        PMID: 8767359

Source DB:  PubMed          Journal:  Arzneimittelforschung        ISSN: 0004-4172


  1 in total

1.  Use of L4 larvae of Nippostrongylus brasiliensis for the in vivo screening of anthelmintic drugs.

Authors:  L Domínguez; J Saldaña; J Chernin
Journal:  Can J Vet Res       Date:  2000-07       Impact factor: 1.310

  1 in total

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