Literature DB >> 8766899

[D-Ala2,D-Leu5]-enkephalin hydrochloride.

J R Deschamps1, C George, J L Flippen-Anderson.   

Abstract

The title compound, L-tyrosyl-D-alanyl-glycyl-L-phenyl-alanyl-D-leucine hydrochloride (C29H40N5O7+. Cl-), co-crystallizes with 2-butanone (C4H8O). The structure determination reveals a slightly distorted type I' beta-bend conformation stabilized by one intramolecular hydrogen bond. This conformation is similar to that observed for other [Leu]-enkephalin analogues.

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Year:  1996        PMID: 8766899     DOI: 10.1107/s0108270196000534

Source DB:  PubMed          Journal:  Acta Crystallogr C        ISSN: 0108-2701            Impact factor:   1.172


  2 in total

1.  The role of crystallography in drug design.

Authors:  Jeffrey R Deschamps
Journal:  AAPS J       Date:  2005-12-07       Impact factor: 4.009

2.  Bioactive conformations of two seminal delta opioid receptor penta-peptides inferred from free-energy profiles.

Authors:  Guido Scarabelli; Davide Provasi; Ana Negri; Marta Filizola
Journal:  Biopolymers       Date:  2014-01       Impact factor: 2.505

  2 in total

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