Literature DB >> 8766176

[Fibrosing cholestatic hepatitis by B virus reactivation in AIDS].

B Poulet1, F Chapel, P Dény, M C Schneider, V Jeantils, M Beaugrand, C Guettier.   

Abstract

We report an Hepatitis B Virus reactivation, in a patient with an end-stage Human Immunodeficiency Virus infection who developed a rapidly progressive liver failure in four months. The main histological features include ballooning of hepatocytes and ground glass transformation, without significant inflammation. Immunohistochemical staining showed a high expression of viral antigens. This case can be related to "Fibrosing Cholestatic Hepatitis", first described after liver transplantation for cirrhosis B. The mechanism of hepatocellular damage is likely to be a direct cytotoxicity of hepatitis B virus.

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Year:  1996        PMID: 8766176

Source DB:  PubMed          Journal:  Ann Pathol        ISSN: 0242-6498            Impact factor:   0.407


  1 in total

1.  Clinicopathological conference: fibrosing cholestatic hepatitis presenting as subacute hepatic failure in a non-transplant patient.

Authors:  Ajay Duseja; Ashim Das; Y K Chawla; Anil Bhansali; V Sakhuja
Journal:  Dig Dis Sci       Date:  2009-07-23       Impact factor: 3.199

  1 in total

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